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This is a multi-centre randomised trial of chemotherapy with chemotherapy plus radioembolisation for colorectal cancer that has spread to the liver

SUMMARY

An open-label randomised phase III trial of 5-Fluorouracil, OXaliplatin and Folinic acid +/- Interventional Radio-Embolisation as first line treatment for patients with unresectable liver-only or liver-predominant metastatic colorectal cancer.

The aim of the trial is to compare chemotherapy alone (5-FU, oxaliplatin & folinic acid) with chemotherapy plus radioembolisation for colorectal cancer that has spread to the liver.

Primary Objectives

  • Overall survival

Trial Publications

The study protocol publication can be found here.

The primary results publication can be found here.

Secondary publications can be found as follows:-