Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Human bone cells, maintained in culture, have been subjected to partitioning in an aqueous two-phase system on a countercurrent distribution apparatus. A broad cell distribution was obtained indicating cell-surface heterogeneity. Two major cell populations were identified which appeared to be growing at different rates. The 'fast'-growing cells had a less hydrophobic cell surface than the 'slow'-growing cells. Possible relationships of these cell populations with osteoblast differentiation and the potential importance of this technique in studies of osteoblast differentiation are discussed.

Original publication

DOI

10.1007/BF01122506

Type

Journal article

Journal

Biosci rep

Publication Date

05/1984

Volume

4

Pages

415 - 419

Keywords

Bone and Bones, Cell Differentiation, Cell Separation, Cells, Cultured, Countercurrent Distribution, Dextrans, Humans, Osteoblasts, Polyethylene Glycols