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The latest updates on our research and how it is improving people’s lives.

Professor Eleanor Stride finalist in prestigious Blavatnik Awards for Young Scientists in the UK

Awards Main

Founder of the awards Sir Leonard Blavatnik said "We are incredibly proud to elevate these select scientists to an international stage that will enable them to be recognised globally, prepare them to become world-class leaders in their scientific fields, and propel the wheel of innovation and societal progress."

New therapeutic target identified in spondyloarthritis

Arthritis Kennedy Main

A new study published in Nature Communications identifies a key driver of joint and intestinal inflammation that could lead to future treatment of the chronic inflammatory disease.

Study reveals how cancer cells use bone marrow fat for growth and survival

Bone oncology Main Research

As society battles with an obesity epidemic, new research from the Edwards group shows how increased body fat contributes to cancer establishment and progression.

Cancer progression may be controlled by targeting tumor-specific extracellular matrix

Kennedy Main Oncology Research

Researchers have uncovered how tumors exploit tenascin-C to deflect the body’s natural defence against them.

Professor Karen Barker recognised in New Year Honours List

Awards Main

The Head of Physiotherapy at NDORMS was awarded an OBE as was Dr Tom Hughes who teaches Emergency Medicine to NDORMS undergraduates.

New collaboration aims to shape future drug development

Botnar Main Research

The EU-PEARL project will take a systematic approach that enables patient-focused, cross company collaborative platform trials.

Flu antiviral has bigger benefits for sicker, older patients

Main

A Europe-wide study conducted over three flu seasons finds that the antiviral drug, oseltamivir (Tamiflu®), can help people recover from flu-like illness about one-day sooner on average, with older, sicker patients who have been unwell for longer recovering two-to-three days sooner.

Researchers identify link in the treatment of inflammatory bowel disease (IBD)

Kennedy Main Research

A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Study reveals ‘postcode lottery’ for hip and knee replacement physiotherapy

Hip Knee Main Research

Post-operation physiotherapy following hip and knee replacement varies significantly across the UK according to new research by Dr Toby Smith, leading to a ‘postcode lottery’ for patients.

Cancer Research UK Senior Fellowship awarded to John Christianson

Funding Main Research

John Christianson, Associate Professor at NDORMS, has been awarded a £2 million Cancer Research UK Senior Cancer Research Fellowship to explore new treatments for patients with multiple myeloma.

New hip fracture study will compare ‘fix’ vs ‘replace’ treatment

Hip Main

A new NIHR funded trial will compare whether either fixing the broken bone or replacing the hip joint gives a better result for people over 60

Double success for David Metcalfe

Awards Hip Main

David Metcalfe has been awarded both the prestigious Syme Medal and the AOUK&I Trauma Research Prize 2019 in recognition of his DPhil work in musculoskeletal science.

Platelet rich plasma found to be of no benefit in treating torn Achilles tendon

Main Publication Research

New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures.

Is surgical repair the best treatment for injuries to the nerves in fingers?

Botnar Hand Main

A new trial, funded by a £1.2 million National Institute of Health Research grant, will explore whether surgery is the best treatment for digital nerve injury.

Two NDORMS researchers receive Versus Arthritis Fellowships

Botnar Funding Main Rehabilitation and self-management Shoulder

Two Versus Arthritis Fellowships have been awarded to NDORMS researchers for the study of frozen shoulder and for management of osteoarthritis among the oldest adults.

NDORMS team awarded the International Dupuytren Award

Awards Hand Kennedy Main

Jagdeep Nanchahal, Professor of Hand, Plastic and Reconstructive Surgery at the Kennedy Institute, and his team have won the International Dupuytren Award for a trial repurposing anti-TNF in Dupuytren’s disease.

New national surgical shoulder trial to investigate repair of partial rotator cuff tendon tears

Botnar Funding Main Shoulder

Professor Jonathan Rees and colleagues in the Surgical Intervention Trials Unit (SITU) have just been awarded a £1.5 million National Institute of Health Research HTA grant for the PRoCuRe trial to explore the benefits of surgical repair of partial rotator cuff tendon tears of the shoulder.

Largest study of its kind provides real-world evidence of the benefits of partial versus total knee replacement

Botnar Knee Main Publication

Opioid use and additional post-operative complications have been shown to be reduced when partial knee replacement is used over surgery where the whole of the joint is replaced.

NIHR success for NDORMS researchers

Awards Botnar Funding Main

Four investigators based at the Botnar Research Centre, NDORMS have been recently awarded National Institute for Health Research (NIHR) fellowships to further our understanding of a variety of musculoskeletal conditions and develop better methodology to support medical research.

Dissecting TNF signalling in inflammatory disease

Inflammation biology Kennedy Main Research

New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

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