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Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.
Buckley Group | Stromal Cell Biology
Inflammation biology Kennedy
We aim to uncover the stromal basis of chronic inflammation and related tissue pathology to target fibroblasts across a range of immune-mediated inflammatory diseases.
Dakin Group | Soft Tissue Joint Disease
Botnar Inflammation biology Orthopaedics and trauma Tissue remodelling and regeneration
The Dakin Group undertakes translational research focusing on identifying the cellular and molecular basis of inflammatory fibrotic soft tissue joint diseases, with research programmes on tendinopathy, frozen shoulder and knee arthrofibrosis. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of inflammatory fibrotic disease.
Clarke Group | Metabolism and Immunity
Inflammation biology Kennedy
Bezbradica Mirkovic Group | Macrophage Biology in Inflammation
Immunity and microbiome Inflammation biology Kennedy
Our research goal is to elucidate mechanisms that control the initiation of inflammatory responses in innate immune cells.
Powrie Group | Mucosal Immunology
Immunity and microbiome Inflammation biology Kennedy
The Powrie lab employs basic and translational science to study host-microbe crosstalk in health and disease, focussing on inflammatory bowel disease (IBD), colorectal cancer (CRC) and inflammatory arthritis. Research spans observational and functional analysis of a broad range of cell types including bacteria, fibroblasts, T cells and neutrophils.