This is a single-centre study in those with high-risk prostate cancer.
\n \n\n \n \nThis is a single centre observational study to evaluate changes in functional images (MRI, Perfusion - CT, & FDG PET) after treatment with chemoradiotherapy.
\n \n\n \n \nThis is a two part, Phase 1 open label dose escalation and expansion study to assess safety, pharmacokinetics and clinical activity of NUC-3373, a nucleotide analogue, in participants with advanced solid tumours.
\n \n\n \n \nMONITOR PsA - Multicentre ObservatioNal Initiative in Treat to target Outcomes in Psoriatic Arthritis
\n \n\n \n \nThis NIHR Programme aims to provide high quality evidence to establish best practice for the management of this common sinus disease. The large multi-disciplinary MACRO research team have come together to tackle the disease from many different aspects \u2013 across primary and secondary care, and from a clinical, economic and patient perspective
\n \n\n \n \nThis is a multi-centre, open label, 2 stage trial in patients with oesophageal cancer
\n \n\n \n \nThis is a study to assess cell therapy as a treatment to prevent kidney transplant rejection. Patients will be randomly assigned to either receive standard medication after transplant or a modified regimen including the cell product.
\n \n\n \n \nCEDAR: Chemoradiation with Enadenotucirev as a radiosensitiser in locally advanced colorectal cancer
\n \n\n \n \nThis is a multi-centre randomised trial of docetaxel with or without AZD6244 in advanced melanoma
\n \n\n \n \nThe PART study is a feasibility study comparing partial ablation (PA) and radical prostatectomy (RP) in men with intermediate risk unilateral prostate cancer. The aim of the feasibility is to determine whether or not it is possible to recruit and randomise men to a trial of this nature.
\n \n\n \n \nClinical effectiveness of symptomatic therapy compared to standard step up care for the treatment of low impact psoriatic oligoarthritis: a 2 arm parallel group feasibility study
\n \n\n \n \nDelivering personalised care in the management of exacerbations of chronic obstructive pulmonary disease: A multi-centre randomised clinical trial.
\n \n\n \n \nThis is a multi-centre, non-randomised trial of gene therapy in those with the condition choroideremia.
\n \n\n \n \nHow can we best address prolonged hospital stays in older inpatients with medical-psychiatric multimorbidity?
\n \n\n \n \nA randomised controlled trial into the effectiveness and efficacy of splints in thumb based osteoarthritis.
\n \n\n \n \nA randomized placebo-controlled study in patients with neurogenic bladder dysfunction and recurrent urinary tract infections (UTIs)
\n \n\n \n \nThis pre-operative window of opportunity study will use functional imaging and serological investigations to assess whether atovaquone significantly reduces tumour hypoxia in patients with non-small cell lung cancer.
\n \n\n \n \nA single arm exploratory study examining the feasibility of imaging glioblastoma pH using CEST MRI
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