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A clinical trial to test a new treatment for Dupuytren’s disease has commenced at the Kennedy Institute and Botnar Research Centre. Affecting 4% of the UK population, this disease causes fingers to curl into the palm and can be extremely disabling.
Botnar Inflammation biology Orthopaedics and trauma Tissue remodelling and regeneration
The Dakin Group undertakes translational research focusing on identifying the cellular basis of inflammatory fibrotic musculoskeletal diseases, with research programmes on tendinopathy and frozen shoulder. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of chronic inflammation and fibrosis.