{ "items": [ "\n\n
This is a multi-centre randomised study investigating ambulatory chest catheter drainage devices in the treament of primary pneumothorax.
\n \n\n \n \nA randomised controlled trial into the effectiveness and efficacy of splints in thumb based osteoarthritis.
\n \n\n \n \nOur aim is to conduct a randomised trial in order to determine the clinical and cost effectiveness of intra-medullary nails versus external fixation for segmental tibial fractures.
\n \n\n \n \nA randomized placebo-controlled study in patients with neurogenic bladder dysfunction and recurrent urinary tract infections (UTIs)
\n \n\n \n \nThis pre-operative window of opportunity study will use functional imaging and serological investigations to assess whether atovaquone significantly reduces tumour hypoxia in patients with non-small cell lung cancer.
\n \n\n \n \nClinical effectiveness of symptomatic therapy compared to standard step up care for the treatment of low impact psoriatic oligoarthritis: a 2 arm parallel group feasibility study
\n \n\n \n \nThis is a multi-centre Phase I trial of pre-operative, margin intensive, stereotactic body radiation therapy (SBRT) for previously untreated borderline resectable pancreatic cancer.
\n \n\n \n \nThis is a multi-centre international Phase 2 trial of Linsitinib in advanced Ewing Sarcoma
\n \n\n \n \nThis is a mechanistic trial of Mifamurtide (MTP-PE) in patients with Metastatic and/or recurrent Osteosarcoma
\n \n\n \n \nINtravenous Iron to Treat Anaemia in CriTical Care Survivors: a feasibility study
\n \n\n \n \nThis is a randomised phase 2 study of paclitaxel with or without GSK1120212 or pazopanib in advanced wt BRAF melanoma
\n \n\n \n \nThis is a single centre trial involving Radiotherapy to see if outcomes can be improved in rectal cancer
\n \n\n \n \nThis is phase 1 multi-centre dose-escalating and safety study of AZD8931 in combination with Oxaliplatin and Capecitabine chemotherapy in patients with Oesophago-gastric adenocarcinoma.
\n \n\n \n \nThe PemBla trial is a parallel group, open label, multi-centre, randomised, phase I/II marker-lesion study of intravesical or intravenous pembrolizumab. The main study will be preceded by a single-institution safety run-in with intra-patient dose escalation of intravesical pembrolizumab performed in paired patient cohorts to confirm the safety and tolerability of intravesical pembrolizumab and the dose to be used in the randomised phase.
\n \n\n \n \nThis was a pragmatic, multi-centre, individually randomised controlled equivalence study with parallel prospective economic evaluation comparing close contact casting technique (CCC) to open reduction and Internal Fixation (ORIF) for patients over 60 years of age with unstable ankle fractures.
\n \n\n \n \nThis trial contacted 490 people who had problems with their hands and wrists as a result of Rheumatoid Arthritis (RA). They then either received usual care (between 1 and 3 sessions of advice with a hand therapist) or the SARAH exercise programme (6 sessions of supervised exercises with a hand therapist).
\n \n\n \n \nThis is a single arm multi-centre NCRI feasibility study of CHOP combined with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter\u2019s syndrome.
\n \n\n \n \nThis is a multi-centre, non-randomised trial of an antibody in patients with acute myeloid leukaemia (AML) or High Risk Myelodysplastic Syndrome (MDS).
\n \n\n \n \nWhat is the rate of deep infection after hip fracture surgery in patients with negative pressure wound therapy compared to standard care wound management?
\n \n\n \n \nA feasibility study to investigate the use of fluorescent lectins to identify dysplasia and cancer during endoscopy and surgery
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