The latest updates on our research and how it is improving people’s lives.
14 November 2017
In a recent study published in The Journal of the American Medical Association (JAMA), research from Oxford Trauma in conjunction with Warwick Clinical Trials Unit shows that intramedullary nail fixation provides better quality of life for patients in the 12 months following a fracture of the distal tibia and costs less than ‘locking’ plate fixation.
4 November 2017
In a new study published in journal Scientific Reports, scientists at NDORMS and the University of Bath have identified a high prevalence of osteoarthritis, hip and knee replacement among former elite rugby players.
23 October 2017
Study of former elite cricketers conducted by scientists at NDORMS highlights the benefits and risks of a career in cricket, including lower heart disease and a high quality of life, but an increased prevalence of osteoarthritis, joint replacement, and mental health conditions.
Blood metal ion thresholds to identify patients with metal-on-metal hip implants at risk of reactions to metal debris
17 October 2017
Research published in The Journal of Bone & Joint Surgery confirms that blood metal ion levels specific to the type of hip implant used can help predict patients who are at low risk of adverse reactions to metal debris (ARMD).
Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation
20 September 2017
Recent research from the Simon Group has discovered an unexpected novel role that autophagy plays during the generation of neutrophils.
8 September 2017
In a new study published in journal Scientific Reports, scientists at NDORMS and Queen Mary University of London have identified reasons underpinning the failure of inflammation to resolve in disorders of musculoskeletal soft tissues such as tendons.
16 July 2017
Researchers at the Kennedy Institute of Rheumatology at the University of Oxford mapped dopamine and the consequences of its release to the immunological synapse.
30 June 2017
UK statisticians and trialists reach out to the clinical trial community in an awareness-raising paper published this week as a first step in changing practice. They promote the use of adaptive designs in early-phase clinical trials to improve trial efficiency, which will benefit patients.
13 April 2017
Evidence released in the Lancet demonstrates a link between patient age and risk of revision on knee and hip replacements.
3 April 2017
A new study published today in Nature Medicine could change the lives of millions of people living with inflammatory bowel diseases (IBD) who don’t respond to the current standard of care.
27 February 2017
Patients who do not respond to current rheumatoid arthritis (RA) treatments may benefit from a new form of treatment that has been shown in a study to be effective against symptoms of the disease.
12 October 2016
Elderly patients with unstable ankle fractures could avoid surgery, according to research by a UK team led by NDORMS at the Oxford University.
9 August 2016
Two Kennedy Institute scientists have proposed a solution to a puzzle of the human immune system: how our immune system scales its response in proportion to any threat to our health to make it 'just right'. Their ideas, published in the journal Trends in Immunology, could support a range of medical research.
5 July 2016
The adoption of new guidance on osteoporosis medication in 2005 may have been responsible for a 22% drop in the number of over-60s suffering a second fracture after a broken hip, an Oxford University study, published in the Journal of Bone and Mineral Research, has found.
28 June 2016
Raising the bar in terms of research excellence - the best studies analysing public health data will soon get better.
28 April 2016
Poorer patients and those who require surgery at the weekend are less likely to receive a total hip replacement (THR), despite clear national guidelines setting out who should get one.
15 April 2016
Trials Journal showcases a new study by NDORMS researchers showing that fall injury prevention trials fail to use a core outcome set.
19 February 2016
BMJ publication on platelet-rich plasma injections for musculoskeletal soft tissue injuries advises against routine use in clinical practice and highlights the need for high quality research.