The latest updates on our research and how it is improving people’s lives.
20 April 2018
Preserving livers at body temperature may improve transplant outcomes and increase viable donor liver numbers, thereby lowering waiting list mortality rates, reports a paper published online this week in Nature.
Study confirms close contact casting offers alternative to surgery in unstable ankle fractures in older people
27 March 2018
A study has confirmed that a new form of casting offers an alternative to invasive surgery in older people who have unstable ankle fractures.
20 December 2017
A recent publication from the Powrie group at the Kennedy Institute of Rheumatology has described a novel mechanism by which the commensal pathogen Heliobacter hepaticus maintains its niche in the intestinal environment.
23 November 2017
Spondyloarthritis encompasses a group of common inflammatory diseases caused by an overactive immune response affecting up to half a million people in the UK alone.
21 November 2017
The role of arthroscopic subacromial decompression in the treatment of subacromial shoulder pain (impingement).
14 November 2017
In a recent study published in The Journal of the American Medical Association (JAMA), research from Oxford Trauma in conjunction with Warwick Clinical Trials Unit shows that intramedullary nail fixation provides better quality of life for patients in the 12 months following a fracture of the distal tibia and costs less than ‘locking’ plate fixation.
4 November 2017
In a new study published in journal Scientific Reports, scientists at NDORMS and the University of Bath have identified a high prevalence of osteoarthritis, hip and knee replacement among former elite rugby players.
23 October 2017
Study of former elite cricketers conducted by scientists at NDORMS highlights the benefits and risks of a career in cricket, including lower heart disease and a high quality of life, but an increased prevalence of osteoarthritis, joint replacement, and mental health conditions.
Blood metal ion thresholds to identify patients with metal-on-metal hip implants at risk of reactions to metal debris
17 October 2017
Research published in The Journal of Bone & Joint Surgery confirms that blood metal ion levels specific to the type of hip implant used can help predict patients who are at low risk of adverse reactions to metal debris (ARMD).
Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation
20 September 2017
Recent research from the Simon Group has discovered an unexpected novel role that autophagy plays during the generation of neutrophils.
8 September 2017
In a new study published in journal Scientific Reports, scientists at NDORMS and Queen Mary University of London have identified reasons underpinning the failure of inflammation to resolve in disorders of musculoskeletal soft tissues such as tendons.
16 July 2017
Researchers at the Kennedy Institute of Rheumatology at the University of Oxford mapped dopamine and the consequences of its release to the immunological synapse.
30 June 2017
UK statisticians and trialists reach out to the clinical trial community in an awareness-raising paper published this week as a first step in changing practice. They promote the use of adaptive designs in early-phase clinical trials to improve trial efficiency, which will benefit patients.
13 April 2017
Evidence released in the Lancet demonstrates a link between patient age and risk of revision on knee and hip replacements.
3 April 2017
A new study published today in Nature Medicine could change the lives of millions of people living with inflammatory bowel diseases (IBD) who don’t respond to the current standard of care.
27 February 2017
Patients who do not respond to current rheumatoid arthritis (RA) treatments may benefit from a new form of treatment that has been shown in a study to be effective against symptoms of the disease.
12 October 2016
Elderly patients with unstable ankle fractures could avoid surgery, according to research by a UK team led by NDORMS at the Oxford University.
9 August 2016
Two Kennedy Institute scientists have proposed a solution to a puzzle of the human immune system: how our immune system scales its response in proportion to any threat to our health to make it 'just right'. Their ideas, published in the journal Trends in Immunology, could support a range of medical research.