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The latest updates on our research and how it is improving people’s lives.

Wellcome Trust Sir Henry Dale Fellowship awarded to Kennedy Researcher

Wellcome Trust Sir Henry Dale Fellowship awarded to Kennedy Researcher

Funding Kennedy Research

We would like to congratulate Dr Luke Jostins-Dean on being awarded a 5-year Sir Henry Dale fellowship, joint funded by the Wellcome Trust and Royal Society, entitled ‘combining genetics and high-resolution cell phenotyping to map pathways underlying inflammatory bowel disease’.

Immune cells are natural networkers

Immune cells are natural networkers

Immunity and microbiome Kennedy Research

New research published in Cell Reports by the Dustin Group has discovered a new way for immune cells to relay information about infection or genetic mutations through dynamic, yet durable cell contacts before deciding how to respond.

Wellcome Trust Investigator Award for Professor Udalova

Wellcome Trust Investigator Award for Professor Udalova

Funding Kennedy Research

Congratulations to Professor Irina Udalova on her successful Wellcome Trust Investigator Award entitled “Molecular control of pathogenic neutrophil responses in inflammation”.

CRUK Fellow joins the Botnar Research Centre

CRUK Fellow joins the Botnar Research Centre

Botnar Funding Research

Congratulations to Siim Pauklin on the award of his CRUK Career Development Fellowship entitled ‘Molecular Mechanisms Regulating Cancer Stem Cell Formation and Maintenance in Pancreatic Cancer’.

A secreted commensal sugar sweetens the deal for intestinal macrophages

A secreted commensal sugar sweetens the deal for intestinal macrophages

Department Kennedy Publication Research

A recent publication from the Powrie group at the Kennedy Institute of Rheumatology has described a novel mechanism by which the commensal pathogen Heliobacter hepaticus maintains its niche in the intestinal environment.

Improved outcomes for patients with fracture of the distal tibia

Improved outcomes for patients with fracture of the distal tibia

Publication Research Trauma

In a recent study published in The Journal of the American Medical Association (JAMA), research from Oxford Trauma in conjunction with Warwick Clinical Trials Unit shows that intramedullary nail fixation provides better quality of life for patients in the 12 months following a fracture of the distal tibia and costs less than ‘locking’ plate fixation.

ImPAcT of inflammation in Achilles tendinopathy

ImPAcT of inflammation in Achilles tendinopathy

Inflammation biology Publication Research

In a new study published in the British Journal of Sports Medicine, scientists at NDORMS investigated if chronic inflammation was a feature of Achilles tendinopathy and rupture.

Study highlights high prevalence of hip and knee replacements for former elite rugby players

Study highlights high prevalence of hip and knee replacements for former elite rugby players

Botnar Publication Research

In a new study published in journal Scientific Reports, scientists at NDORMS and the University of Bath have identified a high prevalence of osteoarthritis, hip and knee replacement among former elite rugby players.

Oxford-Elysium Fellowship in Autophagy

Oxford-Elysium Fellowship in Autophagy

Funding Kennedy Research

Congratulations to Hanlin Zhang for being awarded the first Oxford-Elysium Fellowship in cellular health.

The benefits and risks of a career in cricket

The benefits and risks of a career in cricket

Publication Research

Study of former elite cricketers conducted by scientists at NDORMS highlights the benefits and risks of a career in cricket, including lower heart disease and a high quality of life, but an increased prevalence of osteoarthritis, joint replacement, and mental health conditions.

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation

Autophagy-dependent generation of free fatty acids is critical for normal neutrophil differentiation

Immunity and microbiome Kennedy Publication Research

Recent research from the Simon Group has discovered an unexpected novel role that autophagy plays during the generation of neutrophils.

ARUK award two Clinical Fellowships looking into Osteoarthritis of the Hand.

ARUK award two Clinical Fellowships looking into Osteoarthritis of the Hand.

Botnar Funding Kennedy OACentre Research

Congratulations to our new ARUK Clinical Research Fellows, Dr Malvika Gulati and Miss Jennifer Lane on their successful Fellowship applications.

Targeting tendinopathy resolution

Targeting tendinopathy resolution

Inflammation biology Publication Research

In a new study published in journal Scientific Reports, scientists at NDORMS and Queen Mary University of London have identified reasons underpinning the failure of inflammation to resolve in disorders of musculoskeletal soft tissues such as tendons.

Dopamine rewards immune cells through immunological synapse

Dopamine rewards immune cells through immunological synapse

Immunity and microbiome Publication Research

Researchers at the Kennedy Institute of Rheumatology at the University of Oxford mapped dopamine and the consequences of its release to the immunological synapse.

Kennedy Institute investigator receives MRC Career Development Award

Kennedy Institute investigator receives MRC Career Development Award

Funding Kennedy Research

Dr Anjali Kusumbe has been awarded an MRC Career Development Award to support her research examining how blood vessels support bone growth and repair.

Supporting patient safety through best-practice trial design

Supporting patient safety through best-practice trial design

CSM Publication Research Statistics and epidemiology

UK statisticians and trialists reach out to the clinical trial community in an awareness-raising paper published this week as a first step in changing practice. They promote the use of adaptive designs in early-phase clinical trials to improve trial efficiency, which will benefit patients.

Chris Hyungseop Han receives Award of Excellence from the International Magnesium Association.

Chris Hyungseop Han receives Award of Excellence from the International Magnesium Association.

Awards Botnar Department Research

Chris Hyungseop Han picked up the Award of Excellence at the 74th Annual International Magnesium Association (IMA) World Magnesium Conference held in Singapore last month.

3 new clinical trials for NDORMS

3 new clinical trials for NDORMS

Botnar Funding Orthopaedics, tissue engineering and regenerative medicine Research

NDORMS have been successful with 3 Clinical Trials (BioPatch, MANTIS and NINJA) being awarded.

NDORMS is celebrating World Clubfoot Day today!

NDORMS is celebrating World Clubfoot Day today!

Botnar Orthopaedics, tissue engineering and regenerative medicine Research Translational medicine

More than 30,000 children in Africa are born with clubfoot each year. Many thousands of these children get no treatment, as it is simply not available where they live. They end up with severe deformities that make it hard and very painful to walk.

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