A new NDORMS study supports the hypothesis of immunity debt showing increases of influenza rates one year after global relaxation of COVID-19 restrictions. It highlights the need for proactive preparations in future pandemic response strategies.
The PROBAST+AI guidelines have been updated to provide clearer, more comprehensive standards for evaluating artificial intelligence (AI) models in healthcare research. Originally introduced to assess the risk of bias and the robustness of prediction models, they have been revised to address the growing importance of AI in healthcare decision-making.
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKe, play a crucial role in preventing premature cell death, which can lead to serious inflammation in the body. The findings are particularly relevant for people with a mutation in the TBK1 gene who often develop multiorgan inflammation caused by excessive cell death even in the absence of any infection.
Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering insights into how the interplay between transcriptional and mechanical signals guides processes such as cell fate decisions or the formation of spatially distinct tissue compartments.
Researchers at NDORMS have made an important advancement in the field of single-cell transcriptomics by developing a novel bead design that reduces errors in DNA synthesis and improves the reliability of gene expression measurements.
A new set of guidelines have been launched to create trustworthy AI systems in healthcare. The first of its kind, the FUTURE-AI guideline provides recommendations covering the entire lifecycle of medical AI, from design, development and validation to regulation, deployment, and monitoring.
A grant from the National Institute for Health and Care Research (NIHR) is funding a study to improve healthcare treatment and care for patients with broken bones in three Sub-Saharan Africa countries.
The Translational Pharmacology Group, led by James Fullerton at NDORMS, has announced a significant new partnership with Johnson & Johnson Innovative Medicine to leverage their human experimental medicine platform.
Study shows why there are differences in prognosis between different pancreatic tumours and identifies potential avenues for improved treatment approaches.
A recent study introduces \"Pragmatic Situational Practice Outcomes,\" shedding light on the complexities affecting how patients and healthcare professionals report suspected ADRs related to biologic medications.
Professor Stephanie Dakin has been awarded a Versus Arthritis Bridging Fellowship to advance the work of her Versus Arthritis sponsored Career Development Fellowship investigating frozen shoulder.
Audrey Gerard, an Associate Professor of Immune Cell Dynamics and Principal Investigator at the Kennedy Institute of Rheumatology, is working to understand how the immune response interacts with and shapes tumours.
The\u202fAmerican Association of Immunologists (AAI)\u202fhas recognised the outstanding work of the Kennedy Institute\u2019s Professor of Molecular Immunology Michael Dustin\u202fby naming him a Distinguished Fellow of AAI.
The first ever rheumatologist to be awarded an NIHR Research Professorship, Laura will use the funding to further her research into psoriasis and psoriatic arthritis aiming to transform patient care and treatment personalisation.
A new study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Associate Professor James Fullerton has been awarded Fellowship of the British Pharmacological Society (BPS) following a recommendation by their Honors and Fellows Panel, recognising his sustained contribution to the discipline of Clinical Pharmacology and Therapeutics.
Paul joined the Kennedy Institute in September 2024 as part of the Newton-Abraham Visiting Professorship, a prestigious award given by the University of Oxford to the most distinguished scholars in the biological, chemical or medical sciences.
A new study has revealed that machine learning models can significantly outperform experienced surgeons in predicting patient outcomes after partial knee replacement.
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