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Published in The Lancet Oncology journal, the 10-patient phase 1 clinical trial used focussed ultrasound from outside the body to selectively heat liver tumours and trigger drug release from heat-sensitive carriers, known as thermosensitive liposomes. Building on over a decade of preclinical studies, the study demonstrated the ultrasound technique to be feasible, safe, and capable of increasing drug delivery to the tumour between two-fold and ten-fold in the majority of patients.
MSD Mediation Service
Building better workplace relationships and equipping people to manage conflict better.
New theory for spontaneous reporting of suspected adverse drug reactions to biological therapies
Adverse drug reactions, commonly known as side effects, place a significant burden on health services and account for patient deaths, disease, and extra costs in the UK and worldwide. This research is about the reporting of side effects of biologic medicines on patients.
UK Human Functional Genomics Initiative: Musculoskeletal Cluster
Our research will use genetics to improve our understanding and treatment of musculoskeletal diseases, such as osteoarthritis and carpal tunnel syndrome, which cause more years of disability and pain than any other disease class.
2022-2024 cohort
Find out about our 2022-2024 alumni.