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Men and women working in heavy manual occupations are twice as likely to suffer from knee osteoarthritis (OA), the most common joint disorder, compared to those in sedentary occupations according to a new study published in the prestigious journal Seminars in Arthritis and Rheumatism.
Botnar Inflammation biology Orthopaedics and trauma Tissue remodelling and regeneration
The Dakin Group undertakes translational research focusing on identifying the cellular basis of inflammatory fibrotic musculoskeletal diseases, with research programmes on tendinopathy and frozen shoulder. Understanding the cellular and molecular basis of these diseases will inform new therapeutic approaches targeting tissue resident stromal cells of the joint, to promote resolution of chronic inflammation and fibrosis.