The Bone Cancer Research Trust and Sarcoma UK are joining forces to launch two groundbreaking research projects which could support the early diagnosis of primary bone cancer.
Professor of Orthopaedic Surgery Amar Rangan has been recognised as an exceptional health scientist in his election as a Fellow of the Academy of Medical Sciences.
A team at NDORMS, University of Oxford has successfully administered a pioneering treatment to a patient with XIAP deficiency, a rare genetic disorder.
Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer treatments. This study, published in Cell, demonstrates that engineering T-cells to express both a Chimeric Antigen Receptor (CAR) and a T-cell Receptor (TCR) can improve their ability to distinguish between cancerous and healthy tissues\u2014addressing a major challenge in current immunotherapy.
A new study led by the University of Oxford has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments.
Dr Karthik Ramasamy and team will assess a new mass spectrometry-based monitoring technique for its ability to predict and identify early disease relapse.
Researchers at the University of Oxford have developed a new drug delivery system using ultrasound-activated nanoparticles to break through and destroy bacterial biofilms. This offers a promising solution that could address the global crisis of chronic antibiotic-resistant infections affecting hundreds of millions of people worldwide.
A recent study published in the American Journal of Gastroenterology investigates the incidence and survival rates of colorectal cancer (CRC) in the UK. The research offers healthcare decision-makers crucial insights for planning, management and screening for colorectal cancer.
The CONSORT 2025 statement, an updated guideline for reporting randomised trials is being simultaneously published in The BMJ, JAMA, The Lancet, Nature Medicine, and PLOS Medicine.
A new NDORMS study supports the hypothesis of immunity debt showing increases of influenza rates one year after global relaxation of COVID-19 restrictions. It highlights the need for proactive preparations in future pandemic response strategies.
The PROBAST+AI guidelines have been updated to provide clearer, more comprehensive standards for evaluating artificial intelligence (AI) models in healthcare research. Originally introduced to assess the risk of bias and the robustness of prediction models, they have been revised to address the growing importance of AI in healthcare decision-making.
New research from the Kennedy Institute has revealed how two important proteins, TBK1 and IKKe, play a crucial role in preventing premature cell death, which can lead to serious inflammation in the body. The findings are particularly relevant for people with a mutation in the TBK1 gene who often develop multiorgan inflammation caused by excessive cell death even in the absence of any infection.
Researchers at the Kennedy Institute have developed a new computational framework that allows simultaneous analysis of gene expression and mechanical forces within cells and tissues, uncovering insights into how the interplay between transcriptional and mechanical signals guides processes such as cell fate decisions or the formation of spatially distinct tissue compartments.
Researchers at NDORMS have made an important advancement in the field of single-cell transcriptomics by developing a novel bead design that reduces errors in DNA synthesis and improves the reliability of gene expression measurements.
A new set of guidelines have been launched to create trustworthy AI systems in healthcare. The first of its kind, the FUTURE-AI guideline provides recommendations covering the entire lifecycle of medical AI, from design, development and validation to regulation, deployment, and monitoring.
A grant from the National Institute for Health and Care Research (NIHR) is funding a study to improve healthcare treatment and care for patients with broken bones in three Sub-Saharan Africa countries.
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