NDORMS researchers have identified a critical axis that controls the formation and behaviour of cancer stem cells (CSCs), a subpopulation of cells that influence how lethal the cancer can be, its resistance to chemotherapy, and its ability to spread to other parts of the body.
Alan has spent two months at the Kennedy Institute as a guest of Professor Dame Fiona Powrie. During his visit he has spent his time collaborating with researchers at the Kennedy and other departments in the University, and mentoring young investigators on their career development.
Prof. Michael Dustin was one of 17 researchers from across Oxford's Medical Sciences and Maths, Physics and Life Sciences Divisions that have contributed to a new report on the future of healthcare, compiled by Citi Global Perspectives & Solutions (Citi GPS).
An ongoing research collaboration between NDORMS and University of Birmingham researchers has shown that PEPITEM, a naturally occurring peptide (small protein), holds promise as a new therapeutic for osteoporosis and other disorders that feature bone loss, with distinct advantages over existing drugs.
Researchers have unveiled critical insights into how our genetic makeup influences the body's response to COVID-19 vaccines. The study, published in Nature Communications, may open new paths to personalised vaccination strategies.
Researchers in Oxford have developed a new maternity early warning score that is derived from patient data. The new system, which is being rolled out across the English NHS, will help healthcare providers identify and respond to signs of deterioration in pregnant women.
A new study has provided valuable insights into the ongoing debate surrounding two types of shoulder replacement surgery: reverse total shoulder replacement and anatomical total shoulder replacement as a treatment for patients with osteoarthritis.
A new study has identified that NHS infant checks can miss serious hip abnormalities in new-born babies. Left undetected, these can require complex surgery, and lead to early arthritis. In the UK around 500 infants undergo surgery for dislocated hips which could have been avoidable.
Researchers from NDORMS in collaboration with international institutions have demonstrated the potential of using environmental measurements and deep learning modeling to predict malaria outbreaks in South Asia. The study offers promising insights into improving early warning systems for one of the world's deadliest diseases.
Prof Matt Costa has just returned from the Philippines, where he launched the new HIPCARE trial with co-lead investigator Prof Irewin Tabu. The first of five Low- and Middle-Income Countries (LMIC) in Asia to take part, eight hospitals in the Philippines will start recruiting patients with fragility fractures of the hip to the study within weeks.
NDORMS alumnus Justin Wormald has been awarded an NIHR Academic Clinical Lectureship and an NIHR Development and Skills Enhancement (DSE) Award, as well as being appointed as Deputy Director of the Surgical Trials Intervention Unit (SITU-NDORMS).
The widespread use of artificial intelligence (AI) in medical decision-making tools has led to an update of the TRIPOD guidelines for reporting clinical prediction models. The new TRIPOD+AI guidelines are launched in the BMJ today.
Researchers from NDORMS and the University of Oslo, have successfully replicated findings from recently published international studies on the effectiveness of COVID-19 vaccines to prevent long COVID and post-acute complications.
Connects-UK, a new pan-European network dedicated to advancing scientific collaborations between researchers in the European Union (EU) and the United Kingdom (UK), was officially launched at an event in London yesterday. The network, led by a diaspora of EU researchers working in the UK, seeks to bridge the gap created by Brexit and ensure that collaboration, innovative research, funding, and knowledge exchange continue to thrive in the post-Brexit era.
The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.
NDORMS researchers have conducted a review of the literature on the use of AI in clinical decision-making. Published in the Lancet the study identifies why AI has not yet been taken up more widely, and provides a framework to better inform future adoption and integration of the technology.
A new study published in Nature Human Behaviour sheds light on the long-term mental health consequences of COVID-19 infection and the growing evidence of the protective effect of vaccination on reducing the risk.
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