A Global Grand Challenges case study reveals the potential of large language models (LLMs) to close health gaps in the South Asia, but only when they\u2019re adapted and fine-tuned using local data and expertise.
Researchers at the Kennedy Institute of Rheumatology have found that physically resisting the formation of an immunological synapse actually promotes a stronger immune response. The findings could help explain how immune responses become weakened in cancer and chronic infection and inform the design of more effective vaccines.
Researchers from the University of Oxford have joined African universities and regional experts who are working with Wellcome to establish new science and policy consortiums that will address the escalating public health crisis driven by climate change - saving lives and livelihoods.
Public support for sharing health data for artificial intelligence (AI) research depends on clear public benefit, strong safeguards, and meaningful consent, according to a new NDORMS study based on in-depth focus groups with members of the UK public.
In an editorial piece published in The BMJ, NDORMS Professors David Keene and Matthew Costa commend a new clinical trial that advances the understanding of ankle fracture treatment.
The prospect of long-lasting drug-free remission for children and adults living with inflammatory arthritis is a step closer to becoming a reality, thanks to a new collaboration.
New research carried out by Dr Loren Kell at NDORMS, has demonstrated for the first time that rapamycin can reduce DNA damage in immune cells, a hallmark of ageing.
Oxford Trauma and Emergency Care at Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), along with the Critical Care Research Team at Nuffield Department of Clinical Neurosciences (NDCN) have formally become a new Institute within the University of Oxford: the Kadoorie Institute for Trauma, Emergency and Critical Care.
The use of medications for Attention-Deficit Hyperactivity Disorder (ADHD) has increased substantially across Europe over the past decade, with the steepest rises seen among adults - particularly women - according to a large population-based study published in The Lancet Regional Health \u2013 Europe.
Researchers at NDORMS have found that surgery for a displaced medial epicondyle fracture of the elbow in children offers no clinical benefit compared to non-surgical care. The findings could have significant implications for treatment and offer huge cost savings to the NHS.
Research led by Dr Mariana Borsa at the Kennedy Institute has found that a cellular housekeeping mechanism called autophagy plays a major role in ensuring that T cells generate diverse progenies upon cell division. The findings, published in Nature Cell Biology, could help boost vaccine response in older adults.
Together with a group of Oxford researchers, Mark Coles, Professor of Immunology at the Kennedy Institute, will co-lead the Enabling Next-generation AI for a Bioscience-Led Economy (ENAIBLE) initiative.
The prospect of long-lasting drug-free remission for children and adults living with inflammatory arthritis is a step closer to becoming a reality, thanks to a new collaboration which includes world-leading researchers from the Kennedy Institute.
A collaborative study, which includes contributions from NDORMS researchers Aaron Crowther and supervisor Dario Carugo, explores new ways to model bladder biology and infection, allowing evaluation of antimicrobial therapies under physiologically relevant conditions.
Researchers from the University of Oxford have benchmarked artificial intelligence (AI) tools capable of automatically removing personal information from patient electronic health records (EHRs) in a key step towards enabling large-scale, confidential medical research.
Two research groups at NDORMS have joined the newly launched PROBE initiative, contributing their expertise to a major European collaboration focused on improving the understanding, diagnosis and treatment of osteoarthritis.
Sara Khalid\u2019s Planetary Health Informatics group has been awarded funding from the Gates Foundation\u2019s Grand Challenges initiative to investigate the epidemiology and impact of heavy menstrual bleeding in low-resource settings.
A new national study has found that single-event multi-level surgery (SEMLS) helps straighten the legs and improves walking ability in children with cerebral palsy.
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