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The latest updates on our research and how it is improving people’s lives.

Justin Wormald wins NIHR awards and takes up position as SITU Deputy Director

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NDORMS alumnus Justin Wormald has been awarded an NIHR Academic Clinical Lectureship and an NIHR Development and Skills Enhancement (DSE) Award, as well as being appointed as Deputy Director of the Surgical Trials Intervention Unit (SITU-NDORMS).

New TRIPOD+AI guidelines reflect growing use of AI in healthcare research

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The widespread use of artificial intelligence (AI) in medical decision-making tools has led to an update of the TRIPOD guidelines for reporting clinical prediction models. The new TRIPOD+AI guidelines are launched in the BMJ today.

COVID-19 vaccines effectiveness: results from Norway demonstrate the reproducibility of federated analytics

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Researchers from NDORMS and the University of Oslo, have successfully replicated findings from recently published international studies on the effectiveness of COVID-19 vaccines to prevent long COVID and post-acute complications.

Connects-UK launches to foster scientific collaborations between EU and UK researchers in a post-Brexit era

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Connects-UK, a new pan-European network dedicated to advancing scientific collaborations between researchers in the European Union (EU) and the United Kingdom (UK), was officially launched at an event in London yesterday. The network, led by a diaspora of EU researchers working in the UK, seeks to bridge the gap created by Brexit and ensure that collaboration, innovative research, funding, and knowledge exchange continue to thrive in the post-Brexit era.

New study reveals how T cells gain and maintain tolerance to gut bacteria

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The immune system in the intestine maintains a careful balance, tolerating our long-term resident (commensal) gut bacteria while defending against invading pathogens. Under certain circumstances, dysregulation of our intestinal immune response to commensal and pathogenic microbes can drive inflammatory disease.

Simon Matthew Graham awarded an MRC Clinician Scientist Fellowship

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The award from the Medical Research Council (MRC) will support research to improve treatments for open fractures in low- and middle-income countries.

New framework guides the use of AI for clinical diagnosis

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NDORMS researchers have conducted a review of the literature on the use of AI in clinical decision-making. Published in the Lancet the study identifies why AI has not yet been taken up more widely, and provides a framework to better inform future adoption and integration of the technology.

New study reveals long-term mental health risks after COVID-19

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A new study published in Nature Human Behaviour sheds light on the long-term mental health consequences of COVID-19 infection and the growing evidence of the protective effect of vaccination on reducing the risk.

NDORMS’ Athena Swan Silver award renewed

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NDORMS has been awarded the Athena Swan Silver award for the third consecutive time, recognising the department’s commitment to gender equality.

AI Software yields six-fold increase in spine fracture identification

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Early findings in the ADOPT study, show that Nanox.AI software improves the detection of spine fractures, an early sign of osteoporosis, outperforming UK National Health Service national average.

Professor Gary Collins awarded prestigious NIHR Senior Investigator award

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NDORMS Professor of Medical Statistics and Director of the Centre for Statistics in Medicine, Gary Collins has been appointed National Institute of Health Research (NIHR) Senior Investigator.

New bronchoscopy capability expands capacity for respiratory and vaccine trials

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The NIHR Oxford Clinical Research Facility (EMCRF) hosted by NDORMS has expanded its capability to undertake research bronchoscopies. The facility welcomed its first volunteers as part of the Oxford Airways Study to help understand the causes of asthma.

COVID jab linked to lower risk of COVID-19-related clot and heart complications

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NDORMS research shows that vaccination reduced the risk of heart failure and some clot-related complications for up to a year.

PD-1 gets an “A” for team-work

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A new understanding of the PD-1 axis (programmed death cell) could help shape ongoing efforts to improve treatments for cancer and autoimmune diseases.

Professor Irina Udalova appointed to the MRC’s Infections and Immunity Board

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The Medical Research Council’s Infections and Immunity Board (IIB) funds research into infectious human disease and disorders of the human immune system.

Oxford-ZEISS Centre of Excellence officially opened

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ZEISS is partnering with the University of Oxford bringing ground-breaking microscopy imaging equipment, and analysis tools, to advance the study of global health and disease.

Removing bias from healthcare AI tools

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Rapid advances in Artificial Intelligence (AI) have opened the way for the creation of a huge range of new healthcare tools, but to ensure that these tools do not exacerbate preexisting health inequities, researchers urge the use of more representative data in their development.

Frozen shoulder holds the key to understanding fibrosis resolution

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NDORMS researchers have identified how cells work to resolve frozen shoulder, opening up potential new targets for treatment and reducing the need for surgery.

CRUK funding success for Audrey Gérard

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Audrey Gérard has received £ 1.5 million in funding from CRUK for a new research project to unravel the coevolving cancer and immune landscape.

New research improves accuracy of molecular quantification in high throughput sequencing

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A team at NDORMS has developed a new approach to significantly improve the accuracy of RNA sequencing. They pinpoint the primary source of inaccurate quantification in both short and long-read RNA sequencing, and have introduced the concept of “majority vote” error correction leading to a substantial improvement in RNA molecular counting.

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