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A single arm exploratory study examining the feasibility of imaging glioblastoma pH using CEST MRI

PRIMARY OBJECTIVE

To evaluate CEST contrast image obtained from CEST MRI in glioblastoma

SECONDARY OBJECTIVES

  • Explore if measurement of tumour protein levels relates to CEST MRI imaging signal
  • Explore if measurement of tumour pH relates to CEST MRI imaging signal
  • Explore if hypoxia relates to CEST MRI imaging signal
  • Explore if ASL MRI perfusion imaging signal relates to CEST MRI imaging signal