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Unconventional T cells (UTCs) play important roles in protecting barrier tissues. In this issue of Immunity, Ataide and colleagues show an additional function for these cells: populating downstream lymph nodes and skewing their cytokine profiles. This process allows tissues to adjust the function of draining lymph nodes through imprinting UTC cytokine production, subsequently influencing the immune responses that are triggered.

Original publication

DOI

10.1016/j.immuni.2022.09.008

Type

Journal article

Journal

Immunity

Publication Date

11/10/2022

Volume

55

Pages

1751 - 1753