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It is widely accepted that the likelihood of offspring developing heart disease, stroke, or diabetes in later life, is influenced by the their in utero environment and maternal nutrition. There is increasing epidemiological evidence that osteoporosis in the offspring may also be influenced by the mother's nutrition during pregnancy. This review provides evidence from a range of animal models that supports the epidemiological data; suggesting that lifelong bone development and growth in offspring is determined during gestation.


Journal article


Eur cell mater

Publication Date





321 - 332


Animals, Bone Development, Bone and Bones, Diet, Disease Models, Animal, Female, Fetal Development, Fetal Nutrition Disorders, Humans, Nutritional Requirements, Osteoporosis, Pregnancy