Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Prognostic models are abundant in the medical literature yet their use in practice seems limited. In this article, the third in the PROGRESS series, the authors review how such models are developed and validated, and then address how prognostic models are assessed for their impact on practice and patient outcomes, illustrating these ideas with examples.


Journal article


PLoS medicine

Publication Date





Department of Public Health, Erasmus MC, Rotterdam, Netherlands.


PROGRESS Group, Humans, Disease Progression, Biological Markers, Prognosis, Treatment Outcome, Risk Assessment, Risk Factors, Reproducibility of Results, Predictive Value of Tests, Decision Support Techniques, Models, Theoretical, Biomedical Research, Research Design, Health Services Research, Randomized Controlled Trials as Topic