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Prognostic models are abundant in the medical literature yet their use in practice seems limited. In this article, the third in the PROGRESS series, the authors review how such models are developed and validated, and then address how prognostic models are assessed for their impact on practice and patient outcomes, illustrating these ideas with examples.

Original publication

DOI

10.1371/journal.pmed.1001381

Type

Journal article

Journal

PLoS medicine

Publication Date

01/2013

Volume

10

Addresses

Department of Public Health, Erasmus MC, Rotterdam, Netherlands.

Keywords

PROGRESS Group, Humans, Disease Progression, Prognosis, Treatment Outcome, Risk Assessment, Risk Factors, Reproducibility of Results, Predictive Value of Tests, Decision Support Techniques, Models, Theoretical, Biomedical Research, Research Design, Health Services Research, Randomized Controlled Trials as Topic, Biomarkers