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We looked at our HIV + slow progressors cohort to determine if there were any human leukocyte antigen (HLA) correlates for protection. No statistically significant allelic differences were found between the HIV + and control cohorts using regression analysis, though trends were noted. Data for Elite Controllers showed an increased frequency of B*57. Likewise, no correlation was inferred with the clinical data of the HIV + cohort. We hypothesize that the protective effect of HLA alleles may have been lost over time.

Original publication




Journal article


AIDS (London, England)

Publication Date





2822 - 2824


aNuffield Department of Medicine, John Radcliffe Hospital, Oxford, UK bBeijing You'An Hospital, Capital Medical University, Beijing, China cCentre for Statistics in Medicine, Oxford, UK dSchool of Public Health, Sun Yat-sen University, Guangzhou, China eMRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK fBeijing Ditan Hospital, Capital Medical University, Beijing, China. *Marie-E. Blais and Ke Yi Xu contributed equally to the writing of this article.


Humans, HIV Infections, Phosphoproteins, Cohort Studies, Gene Frequency, HIV Long-Term Survivors, China