Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The aetiology of anal squamous cell carcinoma (SCC) has recently been associated with a sexually transmissible agent--human papillomavirus (HPV) type 16. In this study clinical and pathological data from a prospective series of 67 anal SCC collected over a three year period were compared with the HPV type 16 DNA content of these tumours to determine whether any of the clinical or histological parameters might predict HPV DNA content in a tumour specimen. Of twelve clinicopathological variables examined none was significantly correlated with HPV DNA content at the p = 0.01 level.


Journal article


International journal of colorectal disease

Publication Date





219 - 222


ICRF Colorectal Unit, St. Mark's Hospital, London, UK.


Humans, Papillomaviridae, Carcinoma, Squamous Cell, Anus Neoplasms, DNA, Viral, Analysis of Variance, Multivariate Analysis, Prospective Studies, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male