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OBJECTIVE: To examine the long-term effects of the 'Cretan Health and Nutrition Education Program' on blood pressure. SUBJECTS: A representative population of 176 pupils (85 from the intervention schools and 91 from the control schools). DESIGN: Blood pressure, dietary, anthropometrical and physical activity data were obtained at baseline (academic year 1992-1993) and at follow-up examination (academic year 2001-2002). RESULTS: The findings of the current study revealed that the increase over the 10-year period in systolic (SBP) and diastolic blood pressure (DBP) was higher in the control group (CG) than in the intervention group (IG) (P=0.003 and P<0.001 respectively). Regarding dietary indices, the IG were found to have a significantly higher intake of potassium (P=0.018) and magnesium (P=0.011) compared to the CG. Furthermore, the decrease in body mass index (BMI) z-score observed in the IG was found to differentiate significantly from the increase observed in the CG (P=0.042). On the contrary, the increase in leisure time, moderate to vigorous physical activities (MVPA) observed in the IG, was found to differentiate significantly from the decrease observed in the CG (P=0.032). Intervention's effect on SBP was mediated by changes in MVPA (beta=-0.20, P=0.030) and BMI (beta=0.19, P=0.048). Similarly, intervention's effect on DBP was mediated by changes in MVPA (beta=-0.18, P=0.048), BMI (beta=0.26, P=0.007) and magnesium intake (beta=-0.20, P=0.048). CONCLUSION: The findings of the current study are encouraging, indicating favorable changes in blood pressure, micronutrients intake, BMI and physical activity over the 10 years of follow-up and 4 years after program's cessation, thus providing some support for the effectiveness of school-based health education programs in successfully tackling certain chronic disease risk factors early in life.

Original publication




Journal article


Eur j clin nutr

Publication Date





837 - 845


Adolescent, Adolescent Behavior, Blood Pressure, Body Mass Index, Child, Child Behavior, Diet, Exercise, Female, Follow-Up Studies, Greece, Health Education, Health Promotion, Humans, Leisure Activities, Male, Nutritional Sciences, School Health Services