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This article reviews aspects of respiratory syncytial virus (RSV) infection in airway epithelial cells (AECs), including cytopathogenesis, entry, replication and the induction of immune response to the virus, including a new role for thymic stromal lymphopoietin in RSV immunopathology.

Original publication

DOI

10.1016/j.micinf.2012.11.012

Type

Journal article

Journal

Microbes and infection

Publication Date

03/2013

Volume

15

Pages

230 - 242

Addresses

Millennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Alameda 340, Santiago E-8331010, Chile.

Keywords

Respiratory Mucosa, Epithelial Cells, Animals, Humans, Respiratory Syncytial Viruses, Respiratory Syncytial Virus Infections, Cytokines, Virus Replication, Virus Internalization, Host-Pathogen Interactions