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In this study, a newly developed Mg-Ca-Zn alloy for low degradation rate and surface erosion properties was evaluated. The compressive, tensile, and fatigue strength were measured before implantation. The degradation behavior was evaluated by analyzing the microstructure and local hardness of the explanted specimen. Mean and maximum degradation rates were measured using micro CT equipment from 4-, 8-, and 16- week explants, and the alloy was shown to display surface erosion properties. Based on these characteristics, the average and minimum load bearing capacities in tension, compression, and bending modes were calculated. According to the degradation rate and references of recommended dietary intakes (RDI), the Mg-Ca-Zn alloy appears to be safe for human use.

Original publication

DOI

10.1002/jbm.b.32722

Type

Journal article

Journal

Journal of biomedical materials research. Part B, Applied biomaterials

Publication Date

08/2012

Volume

100

Pages

1535 - 1544

Addresses

Department of Mechanical Engineering, Korea University, Seongbuk, Anam-dong, Seoul, Republic of Korea.

Keywords

Humans, Calcium, Magnesium, Zinc, Alloys, Materials Testing, Absorbable Implants, Stress, Mechanical, X-Ray Microtomography