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We report on methodologies for use in the design of a biodegradable Mg alloy appropriate for load-bearing but temporary orthopedic implant applications. Comparative studies of Mg-5Ca and Mg-5Ca-1Zn were conducted to explore the effects of a combination of minor alloying and hot extrusion, on the alloy's mechanical properties and corrosion resistance. The extruded Mg-5Ca-1Zn exhibited high ultimate compressive strength of 385 MPa and suffered no significant structural degradation even after immersion in simulated body fluid for 30 days. Mg-5Ca-1Zn alloy showed the mechanical strength and controlled corrosion rate to be considered as an ideal candidate for biodegradable orthopedic implant material.

Original publication




Journal article


J biomed mater res b appl biomater

Publication Date





807 - 815


SEM, biodegradation, magnesium, mechanical properties, zinc, Alloys, Compressive Strength, Humans, Magnesium, Materials Testing, Orthopedic Procedures, Weight-Bearing