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We report on methodologies for use in the design of a biodegradable Mg alloy appropriate for load-bearing but temporary orthopedic implant applications. Comparative studies of Mg-5Ca and Mg-5Ca-1Zn were conducted to explore the effects of a combination of minor alloying and hot extrusion, on the alloy's mechanical properties and corrosion resistance. The extruded Mg-5Ca-1Zn exhibited high ultimate compressive strength of 385 MPa and suffered no significant structural degradation even after immersion in simulated body fluid for 30 days. Mg-5Ca-1Zn alloy showed the mechanical strength and controlled corrosion rate to be considered as an ideal candidate for biodegradable orthopedic implant material.

Original publication

DOI

10.1002/jbm.b.33259

Type

Journal article

Journal

Journal of biomedical materials research. Part B, Applied biomaterials

Publication Date

05/2015

Volume

103

Pages

807 - 815

Addresses

Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul, 136-791, Republic of Korea.

Keywords

Humans, Magnesium, Alloys, Orthopedic Procedures, Materials Testing, Compressive Strength, Weight-Bearing