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Sulfites are rarely suspected as causative agents of immediate-type hypersensitivity. We report on a 49-year-old male patient who developed recurrent severe hypotension after food ingestion. A diagnosis of monoclonal mast cell activation syndrome was established. In the double-blind, placebo-controlled food challenge, the patient reacted to potassium metabisulfite with anaphylaxis.

Original publication

DOI

10.1159/000348379

Type

Journal article

Journal

International archives of allergy and immunology

Publication Date

01/2013

Volume

162

Pages

94 - 96

Addresses

Department of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany.

Keywords

Clone Cells, Mast Cells, Humans, Mastocytosis, Anaphylaxis, Food Hypersensitivity, Syndrome, Sulfites, Placebos, Cell Proliferation, Middle Aged, Male