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Sulfites are rarely suspected as causative agents of immediate-type hypersensitivity. We report on a 49-year-old male patient who developed recurrent severe hypotension after food ingestion. A diagnosis of monoclonal mast cell activation syndrome was established. In the double-blind, placebo-controlled food challenge, the patient reacted to potassium metabisulfite with anaphylaxis.

Original publication

DOI

10.1159/000348379

Type

Journal article

Journal

Int arch allergy immunol

Publication Date

2013

Volume

162

Pages

94 - 96

Keywords

Anaphylaxis, Cell Proliferation, Clone Cells, Food Hypersensitivity, Humans, Male, Mast Cells, Mastocytosis, Middle Aged, Placebos, Sulfites, Syndrome