Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The bulk of strong nucleosomes (SNs, with visibly periodic DNA sequences) is described by consensus pattern of 5 or 6 base runs of purines alternating with similar runs of pyrimidines - RR/YY SNs. Yet, the strongest known nucleosome positioning sequence, the 601 clone of Lowary and Widom, is rather periodic repetition of TA dinucleotides following one another every 10 bases. We located "601"-like TA-periodic sequences in the genome of A. thaliana. Several families of such sequences are discovered repeating almost exclusively in centromeres. Thus, while A. thaliana SNs of RR/YY type have strong affinity to pericentromeric regions, as it has been previously found, the SNs of TA periodic type concentrate rather in centromeres.

Original publication

DOI

10.1080/07391102.2015.1028450

Type

Journal article

Journal

Journal of biomolecular structure & dynamics

Publication Date

01/2016

Volume

34

Pages

448 - 451

Addresses

a Genome Diversity Center, Institute of Evolution , University of Haifa , Haifa , Israel.

Keywords

Chromosomes, Plant, Centromere, Nucleosomes, Arabidopsis, DNA, Satellite, Base Sequence, Repetitive Sequences, Nucleic Acid, Base Pairing, Molecular Sequence Data