Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Despite the fundamental importance of measurement in medicine, studies which compare methods of clinical measurement are often analysed inappropriately and may thus come to incorrect conclusions. We explain the problems with the main methods used, notably correlation and regression, and describe the limits of agreement approach which we have proposed. We consider why incorrect methods are so widely used and describe our own experience in bringing this issue to the attention of medical researchers.

Original publication




Journal article


Int j epidemiol

Publication Date



24 Suppl 1


S7 - 14


Clinical Medicine, Data Interpretation, Statistical, Epidemiologic Methods, Humans, Peak Expiratory Flow Rate, Reproducibility of Results, Respiratory Function Tests