Optimal modification of polymer surfaces for calcium phosphate deposition and cell attachment
Choong C., Triffitt J., Cui ZF., Oyane A.
Polycaprolactone (PCL) was surface-modified to optimize calcium phosphate deposition and cell attachment subsequently. It was observed that coating a biopolymer surface such as PCL with calcium phosphate leads to improved cell adhesion and proliferation. The surface modification of the PCL material was done by a chemical procedure that added phosphate end groups to the polymer. The phase of the calcium phosphate particles formed was also found to be similar to that of hydroxyapatite, which was produced by a simple chemical procedure.