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AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.

Journal article

Uğurlu-Çimen D. et al, (2021), Epigenetics chromatin, 14

Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq.

Journal article

Philpott M. et al, (2021), Nat biotechnol

PRMT5 inhibition reduces viability and stemness of pediatric high grade glioma.

Conference paper

Brown EJ. et al, (2021), Cancer research, 81

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection.

Journal article

Sandoval DR. et al, (2021), Biorxiv

Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.

Journal article

Cribbs AP. et al, (2021), Front immunol, 12

Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death.

Journal article

Cottone L. et al, (2020), Cancer res, 80, 4540 - 4551

Advances and challenges in epigenomic single-cell sequencing applications.

Journal article

Philpott M. et al, (2020), Curr opin chem biol, 57, 17 - 26

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.

Journal article

Cribbs AP. et al, (2020), Proc natl acad sci u s a, 117, 6056 - 6066

A Chemical Probe for Tudor Domain Protein Spindlin1 to Investigate Chromatin Function.

Journal article

Fagan V. et al, (2019), J med chem, 62, 9008 - 9025

Alternative angiogenesis mechanisms in uterine fibroids related to heavy menstrual bleeding

Conference paper

Subramaniam KS. et al, (2019), Bjog-an international journal of obstetrics and gynaecology, 126, E125 - E126

Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming.

Journal article

Ebrahimi A. et al, (2019), Nat chem biol, 15, 519 - 528

Alternative Angiogenesis Mechanisms in Uterine Fibroids Related to Heavy Menstrual Bleeding.

Conference paper

Subramaniam KS. et al, (2019), Reproductive sciences, 26, 226A - 227A

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Journal article

Vazquez-Rodriguez S. et al, (2019), Angew chem int ed engl, 58, 515 - 519

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