The MINT trial was led by Professor Sallie Lamb at the University of Warwick. The project was funded by the NIHR Health Technology Assessment programme and involved a randomised controlled trial of treatments for whiplash injuries.
MINT suggested that enhanced psycho-educational interventions in emergency departments are no more effective than usual care advice in reducing the burden of acute whiplash injuries.
A physiotherapy package provided to people who had persisting symptoms within the first 6 weeks of injury produced additional short-term benefits in neck disability compared with a single physiotherapy advice session.
However, from a healthcare perspective, the physiotherapy package was not cost-effective at current levels of willingness to pay. Both experimental treatments were associated with increased cost with no discernible gain in health-related quality of life. However, an important benefit of the physiotherapy package was a reduction in work days lost; consequently, the intervention may prove cost-effective at the societal level.
This trial is closed and results were published in December 2012. Read the final report.
Managing Injuries of the Neck Trial (MINT): a randomised controlled trial of treatments for whiplash injuries.
Lamb SE. et al, (2012), Health technol assess, 16, iii - 141
Development and delivery of a physiotherapy intervention for the early management of whiplash injuries: the Managing Injuries of Neck Trial (MINT) Intervention.
Williamson E. et al, (2009), Physiotherapy, 95, 15 - 23
Managing Injuries of the Neck Trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders.
Lamb SE. et al, (2007), Bmc musculoskelet disord, 8