Contact information
Research groups
Anna Ridley
Postdoctoral Researcher
My research focuses on investigating the phenotype and function of T cells from patients with ankylosing spondylitis and other inflammatory arthritidies. I am using cellular techniques to screen compounds identified by artificial intelligence with the aim of finding new treatments for disease. In addition I have an interest in the innate immune system in ankylosing spondylitis and specifically how neutrophils, an abundant but understudied population, are involved in disease pathogenesis. I joined Paul Bowness’s group in 2009 as a research assistant and undertook my DPhil at the Weatherall Institute of Molecular Medicine.
I am the Human Tissue Officer for the Botnar. In this role I ensure sample collections within the Botnar Research Centre and Nuffield Orthopaedic Centre comply with all regulatory requirements associated with storage of human material for research.
Prior to joining the group I trained as a Clinical Scientist in Immunology at Southampton General Hospital and then was involved in clinical trials monitoring at Oxford BioMedica.
Recent publications
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GM-CSF Primes Proinflammatory Monocyte Responses in Ankylosing Spondylitis.
Journal article
Shi H. et al, (2020), Front immunol, 11
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Pathogenic Th17 signatures in peripheral blood and faecal cytokines of ankylosing spondylitis.
Working paper
Brough I. et al, (2019)
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Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases.
Journal article
Hammitzsch A. et al, (2018), Sci rep, 8
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Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis.
Journal article
Al-Mossawi MH. et al, (2017), Nat commun, 8
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miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.
Journal article
Chen L. et al, (2017), Ann rheum dis, 76, 620 - 625