Contact information
Research groups
Chao-Hui Chang
Postdoctoral Research Assistant
I completed my D.Phil in Nuffield Division of Laboratory Sciences at the University of Oxford in 2013, where my research focused on the interactions between haematopoietic stem cells and the bone marrow niche. After a brief postdoctoral experience and a subsequent career break for primary childcare, I joined Dr Siim Pauklin’s group in 2019 with Daphne Jackson Fellowship to study TGFß signalling in pancreatic cancer stem cells.
My research interests are to identify novel participants in the pathway that shape the cancer stem cell behaviours, leading to new combinational therapeutic targets for TGFβ-relevant diseases.
Recent publications
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Inside the stemness engine: Mechanistic links between deregulated transcription factors and stemness in cancer.
Journal article
Ervin E-H. et al, (2022), Semin cancer biol
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Extracellular Vesicles in Pancreatic Cancer Progression and Therapies
Journal article
Chang C-H. and PAUKLIN S., (2021), Cell death and disease
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ROS and TGFβ: from pancreatic tumour growth to metastasis.
Journal article
Chang C-H. and Pauklin S., (2021), J exp clin cancer res, 40
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Molecular Therapeutics of Pancreatic Ductal Adenocarcinoma: Targeted Pathways and the Role of Cancer Stem Cells.
Journal article
Stoica A-F. et al, (2020), Trends pharmacol sci, 41, 977 - 993
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Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4.
Journal article
Chang C-H. et al, (2016), Stem cells, 34, 1664 - 1678