Chao-Hui Chang

Postdoctoral Research Assistant

I completed my D.Phil in Nuffield Division of Laboratory Sciences at the University of Oxford in 2013, where my research focused on the interactions between haematopoietic stem cells and the bone marrow niche. After a brief postdoctoral experience and a subsequent career break for primary childcare, I joined Dr Siim Pauklin’s group in 2019 with Daphne Jackson Fellowship to study TGFß signalling in pancreatic cancer stem cells.

My research interests are to identify novel participants in the pathway that shape the cancer stem cell behaviours, leading to new combinational therapeutic targets for TGFβ-relevant diseases.

Recent publications

ROS and TGFβ: from pancreatic tumour growth to metastasis.
Journal article

Chang C-H. and Pauklin S., (2021), J exp clin cancer res, 40
Molecular Therapeutics of Pancreatic Ductal Adenocarcinoma: Targeted Pathways and the Role of Cancer Stem Cells.
Journal article

Stoica A-F. et al, (2020), Trends pharmacol sci, 41, 977 - 993
Junctional Adhesion Molecule-A Is Highly Expressed on Human Hematopoietic Repopulating Cells and Associates with the Key Hematopoietic Chemokine Receptor CXCR4.
Journal article

Chang C-H. et al, (2016), Stem cells, 34, 1664 - 1678
A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis
Journal article

Zhou B. et al, (2012), British journal of haematology, 157, 299 - 311
A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis.
Journal article

Zhou B. et al, (2012), Br j haematol, 157, 299 - 311

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