Research Assistant in Statistics
Danielle is currently writing up her thesis, entitled "The association between patterns of glucocorticoid therapy and bone health," which she studied at the University of Manchester under the supervision of Professor Will Dixon. This exposed her to the use of routinely collected data for the assessment of drug safety. During this time she also learnt a relatively new method, the weighted cumulative exposure, which weights drug doses by how recently they were prescribed and hence allows for the comparison of a multitude of patterns of drug use from the same model.
Danielle's current work investigates the effect of bisphosphonate use in patients with chronic kidney disease, once again using routinely collected data. She is soon to start a project investigating the effect of bariatric surgery on fracture risk using the self controlled case series method.
The limitations of using simple definitions of glucocorticoid exposure to predict fracture risk: A cohort study.
Robinson DE. et al, (2018), Bone
Bone Phenotype Assessed by HRpQCT and Associations with Fracture Risk in the GLOW Study.
Litwic AE. et al, (2018), Calcified tissue international, 102, 14 - 22
CLUSTER ANALYSIS OF BONE MICROARCHITECTURE FROM HIGH RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (HR-PQCT) AND FRACTURE IN THE GLOW STUDY
Litwic AE. et al, (2017), OSTEOPOROSIS INTERNATIONAL, 28, S444 - S445
A review of the methods used to define glucocorticoid exposure and risk attribution when investigating the risk of fracture in a rheumatoid arthritis population.
Robinson DE. et al, (2016), Bone, 90, 107 - 115
Cluster analysis of bone microarchitecture from high resolution peripheral quantitative computed tomography demonstrates two separate phenotypes associated with high fracture risk in men and women.
Edwards MH. et al, (2016), Bone, 88, 131 - 137