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Contact information


elizabeth.mann@kennedy.ox.ac.uk

Elizabeth Mann

Postdoc Researcher in Colorectal Cancer

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths world-wide, for which a variety of genetic and environmental risk factors are known to exist. One molecule that is known to promote CRC in mouse models of disease is the Th17-family cytokine IL-23. In human CRC, levels of IL-23 are similarly elevated but it's function in disease progression remains poorly understood.

My research aims to uncover what drives the enhanced production of IL-23 in human CRC tumours and what it is doing at a molecular level.  Insights from these studies will hopefully inform the development of novel diagnostic assays and therapeutics for CRC, particularly focusing on subsets of patients that have poor prognosis.

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