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Chris Hyungseop Han

DPhil Student

Biodegradable Magnesium Alloy for Orthopaedic Application

I did my undergraduate and master's degree in Biomedical Engineering at University of Iowa. After master's degree, I joined Korea Research Institute of Science and Technology as Research Scientist.


Over the past 6 years, I was part of a research team that developed "Biodegradable Metals for Orthopedic Applications". Often a patient has to have two parts of their bones screwed together and most of the times they then have to have a second operation to have the screws removed. So we developed screws which dissolve after they have done their work of knitting together the once broken bones.

We received approval from the KFDA for a clinical trial two years ago and so far over 150+ cases have been successfully performed without any complications (complete degradation of material and bone union after 1 year follow up). Our research was covered recently on the BBC World News as a medical breakthrough (Horizons Series 4 Episode 13). During this time, I was able to conduct various researches and publish several scientific journal papers including several top 5% JCR ranked journals. Furthermore, I never stopped learning and obtained certification in Histotechnology from Indiana University School of Medicine in 2015.

With the completion of first clinical trial, we are still at the very early stage of biodegradable material development process. Current screws aren’t quite as strong as the traditional titanium ones but can be used for broken bones in fingers or fractures in the face. We are in the process of improving the mechanical properties and the application feasibilities are endless.

I believe that the experts from Oxford can provide a whole new insight on how we can use this newly developed material and I am very excited to be here.

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