Research groups
Ines Rombach
Senior Medical Statistician
Passionate about improving the handling and reporting of missing data in randomised controlled trials
As a statistician within the Oxford Clinical Trials Research Unit (OCTRU), I am involved in all aspects of clinical trials.
I contribute statistical expertise to the development of grant applications and to the planning, conduct and analysis of primarily orthopaedic, surgical and antimicrobial trials.
I also hold a researcher post in the Health Economic Research Centre (HERC), where I work on cost-effectiveness analyses alongside randomised controlled trials.
My research interests include the handling and reporting of missing data in randomised clinical trials, the use of patient reported outcomes and surgical trials methodology.
I have been involved in Data Monitoring and Safety Committees as the independent statistician and regularly teach a variety of topics, including aspects of clinical trial design, statistical concepts and statistical programming in Stata.
Key publications
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The current practice of handling and reporting missing outcome data in eight widely used PROMs in RCT publications: a review of the current literature.
Journal article
Rombach I. et al, (2016), Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 25, 1613 - 1623
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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
Journal article
Beard DJ. et al, (2018), The Lancet, 391, 329 - 338
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Impact of a web-based tool (WebCONSORT) to improve the reporting of randomised trials: results of a randomised controlled trial.
Journal article
Hopewell S. et al, (2016), BMC medicine, 14
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Use of placebo controls in the evaluation of surgery: systematic review.
Journal article
Wartolowska K. et al, (2014), BMJ (Clinical research ed.), 348
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Comparison of statistical approaches for analyzing incomplete longitudinal patient-reported outcome data in randomized controlled trials.
Conference paper
Rombach I. et al, (2018), Patient related outcome measures, 9, 197 - 209
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Cost-effectiveness analysis of a placebo controlled randomised surgical trial evaluating the effectiveness of arthroscopic subacromial decompression in patients with subacromial shoulder pain (CSAW)
Journal article
ROMBACH I. et al, The Bone & Joint Journal
Recent publications
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The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation
Journal article
Rooshenas L. et al, (2019), Journal of Clinical Epidemiology, 106, 108 - 120
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Multiple imputation for patient reported outcome measures in randomised controlled trials: advantages and disadvantages of imputing at the item, subscale or composite score level
Journal article
Rombach I. et al, (2018), BMC Medical Research Methodology, 18
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An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment
Journal article
Jepson M. et al, (2018), Journal of Clinical Epidemiology, 99, 75 - 83
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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial
Journal article
Beard DJ. et al, (2018), The Lancet, 391, 329 - 338
-
Comparison of statistical approaches for analyzing incomplete longitudinal patient-reported outcome data in randomized controlled trials
Journal article
Rombach I. et al, (2018), Patient Related Outcome Measures, Volume 9, 197 - 209