Ines Rombach
Senior Medical Statistician
Passionate about improving the handling and reporting of missing data in randomised controlled trials
As a statistician within the Oxford Clinical Trials Research Unit (OCTRU), I am involved in all aspects of clinical trials.
I contribute statistical expertise to the development of grant applications and to the planning, conduct and analysis of primarily orthopaedic, surgical and antimicrobial trials.
I also hold a researcher post in the Health Economic Research Centre (HERC), where I work on cost-effectiveness analyses alongside randomised controlled trials.
My research interests include the handling and reporting of missing data in randomised clinical trials, the use of patient reported outcomes and surgical trials methodology.
I have been involved in Data Monitoring and Safety Committees as the independent statistician and regularly teach a variety of topics, including aspects of clinical trial design, statistical concepts and statistical programming in Stata.
Key publications
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The current practice of handling and reporting missing outcome data in eight widely used PROMs in RCT publications: a review of the current literature.
Journal article
Rombach I. et al, (2016), Qual life res, 25, 1613 - 1623
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Current practice in analysing and reporting binary outcome data-a review of randomised controlled trial reports.
Journal article
Rombach I. et al, (2020), Bmc med, 18
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Oral versus Intravenous Antibiotics for Bone and Joint Infection.
Journal article
Li H-K. et al, (2019), N engl j med, 380, 425 - 436
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Comparison of statistical approaches for analyzing incomplete longitudinal patient-reported outcome data in randomized controlled trials
Journal article
Rombach I. et al, (2018), Patient related outcome measures
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Arthroscopic subacromial decompression for subacromial shoulder pain (CSAW): a multicentre, pragmatic, parallel group, placebo-controlled, three-group, randomised surgical trial.
Journal article
Beard DJ. et al, (2018), Lancet, 391, 329 - 338
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Cost-effectiveness analysis of a placebo-controlled randomized trial evaluating the effectiveness of arthroscopic subacromial decompression in patients with subacromial shoulder pain.
Journal article
Rombach I. et al, (2019), Bone joint j, 101-B, 55 - 62
Recent publications
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Exercise therapy with or without other physical therapy interventions versus placebo interventions for osteoarthritis –systematic review
Journal article
DEAN B. et al, (2021), Osteoarthritis and cartilage open
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Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): statistical analysis plan for a randomised controlled trial assessing the effectiveness of peri-articular liposomal bupivacaine plus bupivacaine hydrochloride compared with bupivacaine hydrochloride alone.
Journal article
Stokes JR. et al, (2021), Trials, 22
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Study of Peri-Articular Anaesthetic for Replacement of the Knee (SPAARK): statistical analysis plan for a randomised controlled trial assessing the effectiveness of peri-articular liposomal bupivacaine plus bupivacaine hydrochloride compared with bupivacaine hydrochloride alone
Journal article
STOKES J. et al, (2021), Trials
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Personalised high tibial osteotomy has mechanical safety equivalent to generic device in a case-control in silico clinical trial
Journal article
MacLeod A. et al, (2021), Communications medicine
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Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design.
Journal article
Rombach I. et al, (2021), Trials, 22
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The clinical and cost effectiveness of splints for thumb base osteoarthritis: a randomised controlled clinical trial
Journal article
ROMBACH I. and DUTTON S., (2020), Rheumatology