James Smith
Postdoctoral Scientist
James is a postdoctoral scientist interested in meta-research, currently focussed on evaluating and improving medical device regulatory pathways.
His MRC funded DPhil was titled “Patent Landscape Reporting Quality and Predicting Drug Approval”, in which he found evidence for poor reporting quality in patent landscapes and developed the reporting items for patent landscapes (RIPL) statement, a reporting guideline. Hoping to reduce the extremely high costs of drug development, he also developed a predictive model which aimed to predict market approval of small molecule compounds from the pre-clinical stage.
He was previously a Research Associate of the CASMI Translational Stem Cell Consortium, where worked on a variety of projects relating to advanced therapeutics, and was a SENS Research Foundation Summer Scholar at the Harvard Stem Cell Institute.
James has a first class undergraduate degree in Biological Sciences from the University of Oxford, where he was an academic scholar at Worcester College.
Key publications
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The Reporting Items for Patent Landscapes statement.
Journal article
Smith JA. et al, (2018), Nat biotechnol, 36, 1043 - 1047
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Evidence of insufficient quality of reporting in patent landscapes in the life sciences.
Journal article
Smith JA. et al, (2017), Nat biotechnol, 35, 210 - 214
Recent publications
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Potential lifetime quality of life benefits of choroideremia gene therapy: projections from a clinically informed decision model.
Journal article
Halioua-Haubold C-L. et al, (2019), Eye (lond), 33, 1215 - 1223
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Bioprocess decision support tool for scalable manufacture of extracellular vesicles.
Journal article
Ng KS. et al, (2019), Biotechnol bioeng, 116, 307 - 319
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The Reporting Items for Patent Landscapes statement.
Journal article
Smith JA. et al, (2018), Nat biotechnol, 36, 1043 - 1047
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Digital health app development standards: a systematic review protocol.
Journal article
Van Velthoven MH. et al, (2018), Bmj open, 8