Kate Coldwell
Contact information
Research groups
Kate Coldwell
PhD, PGCE
Daphne Jackson Trust Fellow
Disentangling the temporal interplay between the liver and gut in primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a rare liver disease with no effective treatment. Its aetiology is complex but likely involves links between the gut, gut microbiome and liver. To understand the disease better, we are studying markers of intestinal inflammation, intestinal permeability and microbiome-derived metabolites in the longitudinal DYNAMHIX in PSC study, asking 'how does disrupted bile flow in PSC affect the gut microbiome, and conversely, how does the disruption to the gut microbiome affect the liver?'
Recent publications
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A novel function for the haemopoietic supportive murine bone marrow MS‐5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis
Journal article
Zhou B. et al, (2012), British journal of haematology, 157, 299 - 311
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A novel function for the haemopoietic supportive murine bone marrow MS-5 mesenchymal stromal cell line in promoting human vasculogenesis and angiogenesis.
Journal article
Zhou B. et al, (2012), Br j haematol, 157, 299 - 311
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Effects of obstetric factors and storage temperatures on the yield of endothelial colony forming cells from umbilical cord blood
Conference paper
Khoo CP. et al, (2012), Vascular pharmacology, 56, 362 - 362
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Effects of obstetric factors and storage temperatures on the yield of endothelial colony forming cells from umbilical cord blood.
Journal article
Coldwell KE. et al, (2011), Angiogenesis, 14, 381 - 392
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Detection of adriamycin-DNA adducts by accelerator mass spectrometry.
Chapter
Coldwell K. et al, (2010), 613, 103 - 118