Milan M. Fowkes
MChem (Warwick); MSc (Western); AMRSC
Imaging of Catabolic and Anabolic Processes for Osteoarthritis Prognosis
I did my undergraduate master's degree in Chemistry (MChem) at the University of Warwick, where I worked on radical cyclisations of N-alkenyl-N-2-bromobenzyl acetamides in my final year research project. I moved to Canada in 2012 to complete a two-year MSc in Chemistry at Western with a specialization in molecular imaging. During that time I synthesized a ghrelin-receptor specific peptidomimetic agonist for imaging of prostatic carcinoma. I presented this work at the 97th Canadian Chemistry Conference and Exhibition (CSC) in Vancouver in 2014. Having developed a strong interest in molecular imaging, I began working as a research assistant in the Lim Lab in 2015, synthesizing a series of radiopaque peptides for the imaging of cartilage breakdown in osteoarthritis. My current research focuses on imaging catabolic and anabolic processes for osteoarthritis prognosis.
Peptidomimetics for imaging the ghrelin receptor
Fowkes MM. and Luyt LG., (2016)
Hou J. et al, (2016), European Journal of Medicinal Chemistry, 123, 822 - 833