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Niamh Richmond

DPhil candidate

I first studied biology and animal physiology as an undergraduate student at the University of Waterloo, in Canada, where I became fascinated with natural sciences underlying corporeal life.  I chose to pursue research within the biological sciences, and obtained a position as technician for the late Professor C.F.M de Lange, testing the effects of nutrition on immune response in piglets. 

My studies in parallel piqued my curiosity for molecular mechanisms underlying disease, thus I pursued a two-year research-based M.Sc. program with Dr. Zia Khan at the University of Western Ontario, investigating the role of Tbx2 on modulating the cell cycle and differentiation of tumour-derived CD133+ stem cells - and what implications this may have for the lifecycle of haemangiomas.  It became apparent that underlying genetic variation and the immune response have unique but intermingling roles in orchestrating disease progression. 

I was subsequently awarded a Clarendon scholarship to pursue my doctoral studies at the University of Oxford, where I’m currently based.  I joined Tal Arnon’s group in 2019, and have since been exploring immunological memory and adaptation during recall viral pulmonary infections.  More specifically, I’m investigating cell signalling pathways that mediate resident memory B cell migration towards sites of infection during influenza rechallenge.  Through advanced microscopy of genetic reporter models, we answer questions regarding lymphocyte migration, activation and residence in pulmonary tissue.  We also use a number of transcriptomic sequencing approaches, antibody therapies, and cytometry techniques to study the inherent biology and function of these newly discovered cells.

Outside of the lab, I like to think big-picture about how advances in life science research can impact human and animal health positively.  I also enjoy playing tennis, painting, and am an avid coffee-enthusiast.