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Pradeep Kumar Sacitharan

Honorary Departmental Researcher

I read my BSc (Honours) in Human and Medical Sciences at the University of Westminster. Afterwards I was awarded a BBRSC funded MRes Studentship at Imperial College London where I studied Experimental Physiology, Drug Discovery and Bio-imaging. Following my masters, I received the Kennedy Prize Studentship to undertake a DPhil in Musculoskeletal Sciences.

My DPhil research is centred on investigating aging processes associated with osteoarthritis. Osteoarthritis is the most common form of arthritis worldwide and patients suffer from severe pain, distress and restricted movement. Age is the primary risk factor for the disease, however, little is known on why the prevalence of osteoarthritis is increased with age.

For the last twenty years, an enzyme called SIRT1 has been extensively shown to control various age-related cellular pathways. My project aims to explore the role of SIRT1 in osteoarthritis and to investigate its therapeutic potential to treat the disease. 

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Recent Publications

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