Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance.

Yap C., Rekowski J., Ursino M., Solovyeva O., Patel D., Dimairo M., Weir CJ., Chan A-W., Jaki T., Mander A., Evans TRJ., Peck R., Hayward KS., Calvert M., Rantell KR., Lee S., Kightley A., Hopewell S., Ashby D., Garrett-Mayer E., Isaacs J., Golub R., Kholmanskikh O., Richards DP., Boix O., Matcham J., Seymour L., Ivy SP., Marshall LV., Hommais A., Liu R., Tanaka Y., Berlin J., Espinasse A., de Bono J.

DOI

10.1136/bmj-2023-076386

Type

Journal article

Publication Date

2023-10-20T00:00:00+00:00

Volume

383

Keywords

Humans, Research Design, Checklist

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