Contact information
Colleges
Sofia Massa
PhD in Statistical Sciences
OCTRU Lead Statistician
Since February 2023 I am a Lead Statistician in the Oxford Clinical Trial Research Unit within the Centre for Statistics in Medicine. I am a member of the senior statistical team and I lead the experimental design and statistical analyses of randomised controlled trials and health research observational studies.
My research interests include advancing statistical methods for experimental design, causal methods for observational studies and the statistical combination of evidence.
I am currently supervising 1 DPhil student and I have supervised 4 DPhil students (in Population Health) to completion and I regularly supervise MSc students.
Previous positions
October 2016-January 2023: Senior Statistician and Module Lead in Statistics (50% Research and 50% Teaching -Nuffield Department of Population Health within the Big Data Institute). I co-lead the statistical and methodological aspects of research studies involving large population studies (UK Biobank, China Kadoorie Biobank, Cuba Prospective Study, Life Line Screening, TILDA among others).
September 2010-September 2016: Departmental Lecturer in Statistics and MSc in Applied Statistics co-ordinator (50% Research and 50% Teaching - Department of Statistics).
Recent publications
Medium-term recovery of patients with complex lower limb fractures : follow-up study of fracture types in the Wound Healing in Surgery for Trauma (WHIST) trial.
Journal article
Goh EL. et al, (2026), Bone Joint J, 108-B, 681 - 687
Agreement and utility between registry and trial mortality data - a data utility comparison in the BOSS trial.
Journal article
Zimmermann A. et al, (2026), Trials, 27
A0644 PRESIDENT: PRostatEctomy Surgery In Disseminated low-volume metastatic hormone sensitive prostate cancer with Endpoint assessment using Nuclear imaging Technology using PSMA (Prostate-Specific Membrane Antigen) PET/CT (Positron Emission Tomography/Computed Tomography) imaging: A definitive randomised controlled trial
Conference paper
Sooriakumaran P. et al, (2026), European Urology, 89, S1 - S1
What is the association between time to surgery and patient outcome after hip fracture? : a systematic review.
Journal article
Mazarello Paes V. et al, (2026), Bone Joint J, 108-B, 30 - 38
Clinical Outcomes of Ultra-Hypofractionated MR-Guided Adaptive SABR (SMART) for Localized Pancreatic Cancer: EMERALD Phase 1 Trial (ISRCTN10557832)
Preprint
Moreno-Olmedo E. et al, (2026)
Real-World Treat-to-Target Strategy in Psoriatic Arthritis: 48-week Results from the MONITOR-PsA Cohort
Preprint
Letarouilly J-G. et al, (2026)
PRESIDENT: PRostatEctomy Surgery In Disseminated low-volume metastatic hormone sensitive prostate cancer with Endpoint assessment using Nuclear imaging Technology using PSMA (Prostate-Specific Membrane Antigen) PET/CT (Positron Emission Tomography/Computed Tomography) imaging: A definitive randomised controlled trial
Conference paper
Sooriakumaran P. et al, (2026), EUROPEAN UROLOGY, 89
Lessons learned from the BOSS trial.
Journal article
Old O. et al, (2025), Lancet Gastroenterol Hepatol, 10, 971 - 972
Cost-Effectiveness of Regular Surveillance Versus Endoscopy at Need for Patients With Barrett's Esophagus: Economic Evaluation Alongside the Barrett's Oesophagus Surveillance Study (BOSS) Randomized Controlled Trial.
Journal article
Deidda M. et al, (2025), Gastroenterology, 169, 1244 - 1252.e7
Barrett's Oesophagus Surveillance Versus Endoscopy at Need Study (BOSS): A Randomized Controlled Trial.
Journal article
Old O. et al, (2025), Gastroenterology, 169, 1233 - 1243.e8
A review of the statistical analysis of randomised controlled trials conducted within OCTRU.
Journal article
Ooms A. et al, (2025), Trials, 26
Su1221: COST-EFFECTIVENESS OF REGULAR SURVEILLANCE VERSUS ENDOSCOPY AT NEED FOR PATIENTS WITH BARRETT’S ESOPHAGUS: ECONOMIC EVALUATION ALONGSIDE THE BOSS RANDOMIZED CONTROLLED TRIAL
Conference paper
Old O. et al, (2025), Gastroenterology, 169
622: BARRETT’S OESOPHAGUS SURVEILLANCE VERSUS ENDOSCOPY AT NEED STUDY (BOSS): A RANDOMIZED CONTROLLED TRIAL
Conference paper
Old O. et al, (2025), Gastroenterology, 169, S - 149
Clinical outcomes from EMERALD trial: A phase I evaluating ultra-hypofractionated MR-Guided Adaptive SABR (SMART) for localized pancreatic cancer
Conference paper
Mukherjee S. et al, (2025), RADIOTHERAPY AND ONCOLOGY, 206, S1783 - S1785
Barrett's Oesophagus Surveillance Versus Endoscopy at Need Study (BOSS): A Randomized Controlled Trial
Journal article
Old O. et al, (2025), GASTROENTEROLOGY, 169
COST-EFFECTIVENESS OF REGULAR SURVEILLANCE VERSUS ENDOSCOPY AT NEED FOR PATIENTS WITH BARRETT'S ESOPHAGUS: ECONOMIC EVALUATION ALONGSIDE THE BOSS RANDOMIZED CONTROLLED TRIAL
Conference paper
Old O. et al, (2025), GASTROENTEROLOGY, 169, S709 - S710
Five-year outcomes for patients sustaining severe fractures of the lower limb from the Wound Healing in Surgery for Trauma (WHIST) trial.
Journal article
Costa ML. et al, (2024), Bone Joint J, 106-B, 858 - 864
The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to severe psoriatic arthritis: the 3-arm parallel group SPEED randomized controlled trial
Journal article
Watson M. et al, (2024), Therapeutic Advances in Musculoskeletal Disease, 16
Anti-TNF (adalimumab) injection for the treatment of pain-predominant early-stage frozen shoulder: the Anti-Freaze-Feasibility randomised controlled trial.
Journal article
Hopewell S. et al, (2024), BMJ Open, 14
The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to severe psoriatic arthritis: the 3-arm parallel group SPEED randomized controlled trial.
Journal article
Watson M. et al, (2024), Ther Adv Musculoskelet Dis, 16