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William Sones

PhD, MSc, BSc

Medical Statistician

Medical statistician and ex-lab researcher

I work with the Oxford Clinical Trials Research Unit (OCTRU), part of the Centre for Statistics in Medicine (CSM) within NDORMS, to provide statistics expertise to support the set-up, management and analysis of clinical trials investigating novel pharmacological treatments and orthopaedic surgical procedures. I also collaborate with Jonathan Cook on the DELTA2 project. The project aims to help researchers calculate the number of subjects required for a trial with guidelines on estimating the amount of change anticipated to be evoked by a treatment.

Before moving into medical statistics, I worked as a post-doctoral research associate specialising in applying patch-clamp electrophysiology to determine cellular mechanisms responsible for controlling nerve firing, muscle contraction and insulin secretion. I've used my experience in both laboratory research and clinical trials to provide guidance for the National Institutes of Health (NIH) in implementing change to the definition of a clinical trial and am a member of the NIHR Statistics Group – Laboratory Studies section.

I obtained an MSc in Applied Statistics from Birkbeck College, University of London in 2011. Prior to this, I graduated with a BSc (Hons) in Toxicology and Pharmacology from the School of Pharmacy, University of London and gained a PhD in Pharmacology from the University of Hertfordshire. I joined NDORMS in 2016.

I was awarded the JSM 2017 Biopharmaceutical Section Best Contributed Paper Award for a presentation entitled Achieving Consensus on Guidance for Specifying the Target Difference in a RCT Sample Size Calculation - DELTA2 Project.

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