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William Sones

OCTRU Medical Statistician

Medical statistician with a keen interest in laboratory based statistics

I contribute statistics expertise to support the set-up, management and analysis of trials investigating novel orthopaedic surgical procedures and pharmacological treatments. I also collaborate with Jonathan Cook on the DELTA2 project. The project aims to assist researchers in calculating the number of subjects required for a trial, which is essential for balancing power against cost. DELTA2 will construct guidelines for estimating the amount of change anticipated to be evoked by a treatment.

Before moving into medical statistics, I worked as a post-doctoral research associate investigating unknown aspects of the cellular mechanisms controlling muscle contraction and insulin secretion. I now apply my extensive laboratory experience as a member of the NIHR Statistics Group – Laboratory Studies section, which is working towards establishing guidelines for improving statistics within laboratory-based research.

I obtained an MSc in Applied Statistics from Birkbeck College, University of London in 2011. In my dissertation research project, I compared the use of non-linear mixed effects modelling and laboratory-based approaches to characterise the inhibitory action of cannabinoids on the gastrointestinal motility. Prior to this, I graduated with a BSc in Toxicology and Pharmacology from the School of Pharmacy, University of London and gained a PhD in Pharmacology from the University of Hertfordshire. I joined the Centre for Statistics in Medicine in 2016.

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