Synovial fluid fingerprinting in end-stage knee osteoarthritis: A novel biomarker concept to assess disease modifying therapies
Jayadev C., Hulley PA., Snelling S., Swales CE., Collins G., Germaschewski F., Taylor PC., Price A.
Osteoarthritis (OA) is a common and debilitating condition with no cure. The lack of disease-modifying treatments is linked to a deficiency in suitable biomarkers. This study aimed to combine multi-molecule synovial fluid analysis with machine learning to produce an accurate diagnostic biomarker model for end-stage knee osteoarthritis.