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The latest updates on our research and how it is improving people’s lives.

Researchers identify link in the treatment of inflammatory bowel disease (IBD)

Kennedy Main Research

A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance

Study reveals ‘postcode lottery’ for hip and knee replacement physiotherapy

Hip Knee Main Research

Post-operation physiotherapy following hip and knee replacement varies significantly across the UK according to new research by Dr Toby Smith, leading to a ‘postcode lottery’ for patients.

Cancer Research UK Senior Fellowship awarded to John Christianson

Funding Main Research

John Christianson, Associate Professor at NDORMS, has been awarded a £2 million Cancer Research UK Senior Cancer Research Fellowship to explore new treatments for patients with multiple myeloma.

New hip fracture study will compare ‘fix’ vs ‘replace’ treatment

Hip Main

A new NIHR funded trial will compare whether either fixing the broken bone or replacing the hip joint gives a better result for people over 60

Double success for David Metcalfe

Awards Hip Main

David Metcalfe has been awarded both the prestigious Syme Medal and the AOUK&I Trauma Research Prize 2019 in recognition of his DPhil work in musculoskeletal science.

Platelet rich plasma found to be of no benefit in treating torn Achilles tendon

Main Publication Research

New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures.

Is surgical repair the best treatment for injuries to the nerves in fingers?

Botnar Hand Main

A new trial, funded by a £1.2 million National Institute of Health Research grant, will explore whether surgery is the best treatment for digital nerve injury.

Two NDORMS researchers receive Versus Arthritis Fellowships

Botnar Funding Main Rehabilitation and self-management Shoulder

Two Versus Arthritis Fellowships have been awarded to NDORMS researchers for the study of frozen shoulder and for management of osteoarthritis among the oldest adults.

NDORMS team awarded the International Dupuytren Award

Awards Hand Kennedy Main

Jagdeep Nanchahal, Professor of Hand, Plastic and Reconstructive Surgery at the Kennedy Institute, and his team have won the International Dupuytren Award for a trial repurposing anti-TNF in Dupuytren’s disease.

New national surgical shoulder trial to investigate repair of partial rotator cuff tendon tears

Botnar Funding Main Shoulder

Professor Jonathan Rees and colleagues in the Surgical Intervention Trials Unit (SITU) have just been awarded a £1.5 million National Institute of Health Research HTA grant for the PRoCuRe trial to explore the benefits of surgical repair of partial rotator cuff tendon tears of the shoulder.

Largest study of its kind provides real-world evidence of the benefits of partial versus total knee replacement

Botnar Knee Main Publication

Opioid use and additional post-operative complications have been shown to be reduced when partial knee replacement is used over surgery where the whole of the joint is replaced.

NIHR success for NDORMS researchers

Awards Botnar Funding Main

Four investigators based at the Botnar Research Centre, NDORMS have been recently awarded National Institute for Health Research (NIHR) fellowships to further our understanding of a variety of musculoskeletal conditions and develop better methodology to support medical research.

Dissecting TNF signalling in inflammatory disease

Inflammation biology Kennedy Main Research

New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.

NDORMS careers event: transitioning from postdoc to PI

Events Main Staff and students

A careers event held by NDORMS offered information and advice to postdoctoral researchers transitioning to becoming independent group leaders.

Professor Eleanor Stride Recognised as one of the 100 Most Influential Women in Engineering

Awards Botnar Main

List produced by Inclusive Boards in partnership with the Financial Times highlights achievements of senior women in engineering

Max Perutz Science Writing Award for Akira Wiberg

Awards Main

NDORMS PhD student Akira Wiberg won the main prize of this year's Max Perutz Science Writing Award. The MRC-funded student received the first prize of £1,500 for his article: "Getting on your nerves.", at the awards ceremony on 15 October.

Pre-clinical study able to regrow bone in myeloma model

Main

New research by the Edwards group and collaborators shows that BMP inhibitors are able to reverse the main untreatable symptom of the disease.

Protective mediators can help heal injured tendon cells by attacking inflammation

Inflammation biology Main Research

Findings reported in The American Journal of Pathology suggest specialized proresolving mediators may become therapeutics that alleviate chronic tendon inflammation

Researchers identify genetic regions associated with left-handedness and link them with brain architecture in language regions

Main

A new study has for the first time identified regions of the genome associated with left-handedness in the general population and linked their effects with brain architecture. The study linked these genetic differences with the connections between areas of the brain related to language.

Naturally occurring compound spermidine boosts vaccine responses in old mice

Kennedy Main

Researchers at the Kennedy Institute identify a molecular pathway to boost vaccine responses in the elderly.

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