The latest updates on our research and how it is improving people’s lives.
NDORMS researchers make Highly Cited Researchers list
19 November 2020
Professor Gary Collins, Professor Cyrus Cooper, Professor Fiona Powrie and the late Professor Doug Altman have been named on the annual Highly Cited Researchers™️ 2020 list from Clarivate.
Professor Katja Simon awarded Wellcome Trust Investigator Award
13 November 2020
Professor Simon has been successful in her Wellcome Trust Investigator Award entitled: “Proteostasis and Autophagy in Immune Senescence.”
HOPE-e study resumes recruitment of women with painful osteoarthritis in the hand
10 November 2020
Researchers in Oxford are looking to recruit women who have painful osteoarthritis in joints of their hands, after resuming a study that was paused due to the COVID crisis.
NDORMS staff recognised for excellence in teaching and research
5 November 2020
Three NDORMS researchers have been awarded new titles in the University of Oxford's 2020 Recognition of Distinction exercise.
European Centre of Excellence at NDORMS
3 November 2020
NDORMS has been designated a EULAR Centre of Excellence 2020-2025, in recognition of our continued high-quality research publications in rheumatology.
Size does matter
2 November 2020
Researchers from the Universities of Oxford, Nottingham and Zhejiang have found that the precise measurement of joint lining inflammation corresponds well with osteoarthritic knee pain. It's even better when size of the joint is taken into consideration and this should be considered when examining treatment effects in clinical trials.
An unexpected repair function for neutrophils
30 October 2020
In a collaboration with scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), Kennedy researchers have contributed to the discovery that neutrophils have many more functions in the body than previously thought. This finding suggests that neutrophil tissue-specific plasticity could be exploited in designing new treatments for neutrophil driven diseases, including cancer.
Ethnic representation within the Tendon Human Cell Atlas to be improved with Chan Zuckerberg Initiative funding
29 October 2020
NDORMS researchers have been awarded funding from the Chan Zuckerberg Initiative to ensure that tendon samples from understudied ethnic groups are included in the Tendon Human Cell Atlas.
Knee OA guidance for clinicians simplified and streamlined
28 October 2020
Researchers review the similarities and differences between OARSI and ESCEO 2019 guidelines for the management of knee OA and provide a narrative to help steer health-care providers through the complexities of non-surgical management of the disease.
Understanding the physics of the immune response necessitates new technology
23 October 2020
Professor Marco Fritzsche has joined the Kennedy Institute as the Principal Investigator of the Biophysical Immunology Laboratory (BPI), as part of a joint appointment with the Rosalind Franklin Institute. His lab is leading the development of a lattice light sheet microscope that will significantly advance the study of live cells.
CD2 corolla calls T cells to arms
20 October 2020
A team from the University of Oxford has visualised how key cells of the immune system lock onto cancerous or infected cells to destroy them. The work was led by the Mike Dustin’s group at the Kennedy Institute of Rheumatology and experts in colorectal and ovarian cancers from across Oxford and computational biologists at the University of Birmingham.
Likely culprits causing blood vessel lesions in vasculitis identified
19 October 2020
NDORMS researchers identify a subset of immune cells that could be a new therapeutic target to treat inflamed blood vessels in Giant Cell Arteritis (GCA) and other forms of inflammatory vascular disease.
Review of proposed FDA regulation reveals the extent of financial ties to industry
15 October 2020
A review of public comments on a proposed FDA regulatory framework, for modifications to artificial intelligence and machine learning-based software as a medical device, has found that 63% came from parties with financial ties to industry, and that the majority, 86% did not cite any scientific evidence.
Professor Stride announced as Honorary Fellow of IET
8 October 2020
Institution of Engineering and Technology announces 16 Honorary Fellows to mark its 150th year. Professor Stride was awarded the Fellowship in recognition of her contribution to biomedical engineering and research into treatment of major diseases.
Carpal tunnel decompression surgery found to be a safe option for patients
7 October 2020
One of the leading causes of workplace absence, carpal tunnel syndrome, can be treated successfully with decompression surgery without serious complications according to research from NDORMS.
Hospitalised COVID-19 patients shown to be younger and healthier than flu patients
6 October 2020
Patients hospitalised with COVID-19 were more likely male, younger and, in both the US and Spain, had fewer comorbidities and lower medication use than hospitalized influenza patients according to a recent study published recently by the Observational Health Data Sciences and Informatics (OHDSI) community.
Research review reveals potential to improve colon cancer treatments
2 October 2020
Researchers at the Kennedy Institute review the growing body of literature on the role of the microbiome in colorectal cancer
Oxford researchers start new trial on the use of anti-TNF to treat Covid-19 in care homes
30 September 2020
Researchers at the University of Oxford are starting a new study to explore the effectiveness of the anti-tumour necrosis factor (anti-TNF) drug adalimumab as a treatment for patients with COVID-19 in the community, especially care homes. The AVID-CC trial, which will be conducted by Oxford Clinical Trials Research Unit (OCTRU), will enrol up to 750 patients from community care settings throughout the UK.
Professor Chris Lavy awarded prestigious honorary fellowship by British Orthopaedic Association
23 September 2020
Professor of Orthopaedic and Tropical Surgery and Consultant Orthopaedic and Spine Surgeon Chris Lavy has been awarded a prestigious honorary fellowship by the British Orthopaedic Association (BOA).
Key discovery in Psoriatic Arthritis points way for developing targeted treatments
21 September 2020
A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the strongest evidence yet of a single cause for the disease.