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The NIHR Biomedical Research Centre, Oxford (OxBRC) is based at the Oxford University Hospitals NHS Foundation Trust and run in partnership with the University of Oxford. The OxBRC brings together the research expertise of the University of Oxford and the clinical skills of staff of Oxford University Hospitals NHS Foundation Trust with the aim of supporting translational research and innovation to improve healthcare for patients.

Oxford BRC is divided into 20 themes and four Clusters: Precision Medicine, Technology and Big Data, Immunity and Infection and Chronic Diseases:



The Musculoskeletal Theme

The NIHR BRC Musculoskeletal theme is led by Professor Andrew Carr and includes our three world-leading research institutes – the Botnar Institute for Musculoskeletal Sciences, the Kennedy Institute for Rheumatology and the Kadoorie Centre. It also incorporates the internationally recognised Centre for Statistics in Medicine and the accredited Oxford Clinical Trials Research Unit, as well as the NIHR Thames Valley Clinical Research Network, and plays a lead role in the NIHR Translational Research Collaborations in inflammatory joint and rare bone diseases.

The Musculoskeletal theme encompasses inflammatory joint disease, trauma, degenerative joint disorders and rare bone diseases. We will build upon our established and proven strengths in identifying new pharmacological, surgical and rehabilitation treatments and accelerating their translation to the clinic. We will also further develop Oxford’s promising tissue engineering implants and devices for the benefit of patients. The Musculoskeletal is embedded within the Technology and Big Data cluster of the OxBRC and interacts strongly with themes within the Precision Medicine, Immunity and Infection and Chronic Disease clusters.

The work of the Musculoskeletal Theme of OxBRC is focussed around five interacting areas, all underpinned by their significant impact on society: 

NIHR Biomedical Research Centre sub themes


The overarching aim of the Musculoskeletal theme is to use cutting edge methodologies to drive translational research in musculoskeletal science with the ultimate goal of improving outcomes for patients with musculoskeletal disease. 

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