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Dr Laura Coates has been awarded £1.8M from the National Institute for Health Research (NIHR) to explore the potential for precision medicine in the choice of biologics to reduce inflammation and pain in psoriatic arthritis.
Cognitive–behavioural therapy consistently improves quality of life
Main Rehabilitation and self-management Research
26 February 2021
A meta-review of the available research into cognitive behavioural therapy reveals it consistently improves health-related quality of life across different medical conditions and demographic populations.
Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders
Main Research
19 February 2021
The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
WHiTE Four trial results published
Hip Main OCTRU Orthopaedics and trauma Research
9 February 2021
The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.
Understanding the first wave of COVID-19 and implications for tackling the ongoing pandemic: evidence from 5.5 million people from Catalonia, Spain
Botnar Main Research Statistics and epidemiology
3 February 2021
Health outcomes during the first wave of COVID-19 in Catalonia, Spain, have been described in detail in a study published by Nature Communications.
Immunology preprint reviews launched in Nature Reviews Immunology
Kennedy Main Research
15 January 2021
The Oxford-Mount Sinai (OxMS) Preprint Journal Club has partnered with Nature Reviews Immunology to launch a monthly Preprint Watch column.
Living reviews launched by Oxford and Cardiff in the wake of COVID-19 research
Kennedy Main Research
18 December 2020
In a combined effort to help COVID-19 researchers the University of Oxford and Cardiff University have launched a series of “living reviews” in Oxford University Press’s new open access journal “Oxford Open Immunology”.
3D imaging reveals the role of blood vessels in hormone production
Kennedy Main Research
11 December 2020
New research from the Kusumbe Group at the Kennedy Institute has shown a direct correlation between age-related decline in capillary and artery numbers and hormone production in the endocrine system.
Could do better: clinical trial reporting fails to live up to the mark
CSM Main OCTRU Research
8 June 2020
The statistical analysis and reporting of treatment effects in reports of randomised trials with a binary primary endpoint requires substantial improvement, suggests NDORMS research published in BMC Medicine.
Study reveals how cancer cells use bone marrow fat for growth and survival
Bone oncology Main Research
17 January 2020
As society battles with an obesity epidemic, new research from the Edwards group shows how increased body fat contributes to cancer establishment and progression.
Cancer progression may be controlled by targeting tumor-specific extracellular matrix
Kennedy Main Oncology Research
15 January 2020
Researchers have uncovered how tumors exploit tenascin-C to deflect the body’s natural defence against them.
New collaboration aims to shape future drug development
Botnar Main Research
18 December 2019
The EU-PEARL project will take a systematic approach that enables patient-focused, cross company collaborative platform trials.
Researchers identify link in the treatment of inflammatory bowel disease (IBD)
Kennedy Main Research
6 December 2019
A new study published in the Journal of Experimental Medicine reveals how IL-10 and PGE2 work together to prevent inflammatory tissue damage and maintain a healthy gut balance
Study reveals ‘postcode lottery’ for hip and knee replacement physiotherapy
Hip Knee Main Research
5 December 2019
Post-operation physiotherapy following hip and knee replacement varies significantly across the UK according to new research by Dr Toby Smith, leading to a ‘postcode lottery’ for patients.
Cancer Research UK Senior Fellowship awarded to John Christianson
Funding Main Research
2 December 2019
John Christianson, Associate Professor at NDORMS, has been awarded a £2 million Cancer Research UK Senior Cancer Research Fellowship to explore new treatments for patients with multiple myeloma.
Platelet rich plasma found to be of no benefit in treating torn Achilles tendon
Main OCTRU Publication RRIO Research
20 November 2019
New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures.
Dissecting TNF signalling in inflammatory disease
Inflammation biology Kennedy Main Research
28 October 2019
New research from Dr Richard Williams’ group at the Kennedy Institute suggests a route for the development of more selective – and effective – therapies for immune-mediated inflammatory disease.
Protective mediators can help heal injured tendon cells by attacking inflammation
Inflammation biology Main Research
11 October 2019
Findings reported in The American Journal of Pathology suggest specialized proresolving mediators may become therapeutics that alleviate chronic tendon inflammation
Increased use of partial knee replacement could save the NHS £30 million per year
Botnar Knee Main Publication Research SITU Trials
17 July 2019
New research from a randomised clinical trial published today in The Lancet and funded by the National Institute for Health Research (NIHR) shows that partial knee replacements (PKR) are as good as total knee replacements (TKR), whilst being more cost effective.
Vaccine developed to treat osteoarthritic pain
Kennedy Main OACentre Publication Research
12 March 2019
Researchers have developed a vaccine that blocks the effects of the main cause of pain in osteoarthritis (OA) - nerve growth factor (NGF) - in mice.
Genes and height matter for carpal tunnel syndrome
Botnar Main Publication Research
4 March 2019
Researchers from the University of Oxford and Estonia have found further evidence that a person’s genetic make-up and height can influence whether they will develop carpal tunnel syndrome (CTS).
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Laura Coates
NIHR Clinician Scientist and Senior Clinical Research Fellow
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Similar stories
New centre aims to help companies conduct more efficient trials
26 February 2021
A new clinical therapeutics centre has been set up by the University of Oxford to help life sciences companies identify interventions that have the greatest potential to deliver patient benefit, and so bring down the cost of early phase clinical trials.
Cognitive–behavioural therapy consistently improves quality of life
26 February 2021
Main Rehabilitation and self-management Research
A meta-review of the available research into cognitive behavioural therapy reveals it consistently improves health-related quality of life across different medical conditions and demographic populations.
Oxford to collaborate with Janssen to map the cellular landscape of immune mediated disorders
19 February 2021
The University of Oxford has entered into a strategic collaboration with Janssen Biotech, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.
Versus Arthritis Foundation Fellowship awarded to Dr Kristina Zec
19 February 2021
Dr Kristina Zec has been awarded a Versus Arthritis Foundation Fellowship to investigate the role of products of lipid oxidation produced by synovial macrophages in triggering articular inflammation.
Study reveals the safety of bisphosphonates in chronic kidney disease
10 February 2021
The results of an observational study published in JMBR and funded by the Health Technology Assessment Programme shows that bisphosphonate use is associated with a greater risk of chronic kidney disease progression.
WHiTE Four trial results published
9 February 2021
Hip Main OCTRU Orthopaedics and trauma Research
The results of the WHiTE Four clinical trial for the treatment of fragility hip fractures have been published in The Bone and Joint Journal.